Results 61 to 70 of about 25,693 (232)
LDLR, LRP1, and Megalin redundantly participate in the uptake of Clostridium novyi alpha-toxin
Communications Biology, 2022 Clostridium novyi alpha-toxin (Tcnα) also uses LRP1 and Megalin as cellular entry receptors besides LDLR, and this might be a response to cell-type dependent receptor availability for the exotoxin.
Yao Zhou +6 more
doaj +1 more source
Pseudomonas exotoxin: chimeric toxins
Journal of Biological Chemistry, 1989 Pseudomonas exotoxin binds to and enters cells by receptor-mediated endocytosis. Within the cell it requires exposure to low pH to enable it to translocate to the cell cytoplasm where it inhibits protein synthesis by ADP-ribosylating elongation factor 2.
I, Pastan, D, FitzGerald
openaire +2 more sources
Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in dynamics: an animal model in white mice [PDF]
Саратовский научно-медицинский журнал, 2015 Purpose: to study biochemical indices of peripheral blood which show organs functional changes. Material and Methods. The experiments were carried out on white mice in dynamics development of pseudomonas aeruginosa caused by intraperitoneal injection of ...
Morrison A.V. +2 more
doaj
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Phage therapy shows promising efficacy against MDR, XDR, and PDR Pseudomonas aeruginosa infections across different models and administration routes. Evidence highlights reduced mortality, bacterial clearance, and synergy with antibiotics, while emphasizing the need for standardized protocols and advanced delivery systems to support clinical ...
Gustavo Aparecido da Cunha +7 more
wiley +1 more source
Toxins, 2017 Pseudomonas aeruginosa exotoxin A (PEA) causes severe hepatotoxicity in experimental animals and is useful in investigations of immune-mediated liver injury.
Chien-Chao Chiu +7 more
doaj +1 more source
The future of antiviral immunotoxins [PDF]
, 2016 There is a constant need for new therapeutic interventions in a wide range of infectious diseases. Over the past few years, the immunotoxins have entered the stage as promising antiviral treatments.
Høy Jakobsen, Mette +3 more
core +1 more source
Public Health Challenges, Volume 5, Issue 2, June 2026.Diphtheria vaccination coverage among Nigerian children remains suboptimal (56%). Coverage is significantly lower in Northern states and inversely correlated with multidimensional poverty. Addressing poverty‐related deprivations is essential to improving immunization equity and curbing recurrent diphtheria outbreaks.
Olufemi Olulaja, Rana Jaber
wiley +1 more source
Clinical and Translational Allergy, Volume 16, Issue 5, May 2026.ABSTRACT Introduction Chronic rhinosinusitis (CRS) pathophysiology and its link to microbiome is an area of ongoing investigation. Certain pathogens, in particular Staphylococcus aureus described to contribute to recalcitrant CRS. In addition, different species of coagulase negative staphylococci (CoNS) are frequently isolated from the sinonasal cavity
Sintayehu Ambachew +9 more
wiley +1 more source
Journal of Fasa University of Medical Sciences, 2015 Background & Objective: Dendritic cell (DC) is as a key cell in activation of immune response against microbes and disease. Therefore, the effect of recombinant exotoxin A of Pseudomonas aeruginosa on the maturity and the activation of DCs was evaluated ...
Mohammad Hossein Karimi +3 more
doaj
Partial purification and properties of plasmonigen fractionated from horse serum and activated via staphylokinase [PDF]
, 1951 Thesis (M.A.)--Boston ...
Kaplan, Carl
core +1 more source