Results 61 to 70 of about 113,929,087 (168)

DBETH: A Database of Bacterial Exotoxins for Human [PDF]

Nucleic Acids Research, 2011
Pathogenic bacteria produce protein toxins to survive in the hostile environments defined by the host's defense systems and immune response. Recent progresses in high-throughput genome sequencing and structure determination techniques have contributed to a better understanding of mechanisms of action of the bacterial toxins at the cellular and ...
Abhijit Chakraborty 0003, Sudeshna Ghosh, Garisha Chowdhary, Ujjwal Maulik, Saikat Chakrabarti 0001   +4 more
openaire   +2 more sources

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Exotoxin Secretion: Getting Out to Find the Way In [PDF]

, 2008
SummaryDuring infection, most pathogenic bacteria deliver proteins to the host cell cytoplasm to manipulate host behavior. In this issue of Cell Host & Microbe, Spanò and colleagues describe a system where a bacterium produces an exotoxin while inside ...
Bischofberger, Mirko, van der Goot, F. Gisou   +1 more
core   +2 more sources

The Immunomodulatory Effect of Recombinant Exotoxin A of Pseudomonas Aeruginosa on Dendritic Cells Extracted from Mice Spleen

Journal of Fasa University of Medical Sciences, 2015
Background & Objective: Dendritic cell (DC) is as a key cell in activation of immune response against microbes and disease. Therefore, the effect of recombinant exotoxin A of Pseudomonas aeruginosa on the maturity and the activation of DCs was evaluated ...
Mohammad Hossein Karimi, Aziz Japoni, Manouchehr Rasouli, Salimeh Ebrahimnezhad   +3 more
doaj  

LDLR, LRP1, and Megalin redundantly participate in the uptake of Clostridium novyi alpha-toxin

Communications Biology, 2022
Clostridium novyi alpha-toxin (Tcnα) also uses LRP1 and Megalin as cellular entry receptors besides LDLR, and this might be a response to cell-type dependent receptor availability for the exotoxin.
Yao Zhou, Danyang Li, Diyin Li, Aizhong Chen, Liuqing He, Jianhua Luo, Liang Tao   +6 more
doaj   +1 more source

Molecular Detection of tox A Gene in Multidrug Resistance Pseudomonas aeruginosa Isolated from Burn Infections

Medical Journal of Babylon
Background: Exotoxin A (ExoA) is the most widespread and toxic virulence agent among pathogenic Pseudomonas aeruginosa species that acquire adenosine diphosphate-ribosyltransferase activity belonging to the class of exotoxins secreted by pathogenic ...
Zahraa Hamza Merza, Rabab Omran
doaj   +1 more source

Bacterial Diseases in Farmed Nile Tilapia (Oreochromis niloticus): A Review of Pathogenesis, Immune Responses and Recent Advances in Diagnostics and Management

Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.
Pathogenesis of bacterial diseases in Nile tilapia and anti‐bacterial mechanisms. ABSTRACT Nile tilapia (Oreochromis niloticus) is among the most widely farmed fish globally that plays a major role in ensuring food security in many low‐ and middle‐income countries.
Catherine Agoe, John Walakira, Gerald Kwikiriza, Nasser Kasozi, Ivan Abaho, Manuel Curto, Paul Meulenbroek, Harald Meimberg, Peter Akoll   +8 more
wiley   +1 more source

Pasteurella haemolytica exotoxin : chemical, biological, and immunological characterization of a leukotoxin produced by P. haemolytica

, 1984
Typescript (photocopy).Pasteurella haemolytica pneumonia is recognized as an economically important constituent of the group of bovine respiratory disease problems collectively referred to as the bovine respiratory disease complex, and as an important ...
Chang, Yung-F
core   +1 more source

Quercus infectoria gall extracts reduce quorum sensing-controlled virulence factors production and biofilm formation in Pseudomonas aeruginosa recovered from burn wounds

BMC Complementary and Alternative Medicine, 2019
Background Quercus gall extracts’ ability to kill pathogens in vitro and even removal of chronic drug-resistant infections has been reported by several studies.
Akhter Ahmed Ahmed, Fraidoon Abdulqadir Salih   +1 more
doaj   +1 more source

Multifaceted Suppression of Staphylococcal Virulence Phenotypes: In Vitro Study of a Cellular Status With Reduced Agr Activity and Impaired Biofilm

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Finding of in vitro S. aureus status with reduced Agr activity and impaired biofilm. ABSTRACT Anti‐quorum sensing (QS) therapy has been focused on to reduce the virulence of pathogenic bacteria. However, there is a risk that suppression of the staphylococcal QS Agr system might promote biofilm formation.
Nghi Bao Nguyen, Yuri Ushijima, Raiku Sekiya, Kazuya Morikawa, Le Thuy Thi Nguyen   +4 more
wiley   +1 more source