MedComm, Volume 6, Issue 11, November 2025.Significance: Immune‐controlled dormant metastases exhibit a unique phenotype, primarily promoted by the Ch25h gene, that can be exploited to discover new biomarkers, as well as the development of therapies to eradicate dormant metastases or control overt metastases.
Virginia Chamorro +10 more
wiley +1 more source
Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction. II. Fine specificity of effector T cell inhibition. [PDF]
, 1992 Litjen Tan, Mark Kennedy, S. D. Miller
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MedComm, Volume 6, Issue 11, November 2025.Mucosa‐associated invariant T (MAIT) cells are an evolutionarily conserved class of innate‐like T lymphocytes that rely on MR1 molecules to recognize microbial metabolites and play a central role in immune surveillance and inflammatory regulation.
Cheng Zhu +10 more
wiley +1 more source
Inhibition of experimental autoimmune encephalomyelitis by MHC class II binding competitor peptides depends on the relative MHC binding affinity of the disease-inducing peptide. [PDF]
, 1994 Marca H. M. Wauben +5 more
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European Journal of Neurology, Volume 32, Issue 11, November 2025.The review analyzed 87 studies from 20 countries on environmental risk factors for MS. EBV infection increased MS risk, while breastfeeding showed limited protection. Adverse social experiences, active smoking, and obesity in childhood/adolescence raised risk, whereas normal BMI was protective.
Bruno Kusznir Vitturi +8 more
wiley +1 more source
Microglia P2X4 receptors as pharmacological targets for demyelinating diseases
EMBO Molecular Medicine, 2018 Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis.
Francesco Di Virgilio, Alba Clara Sarti
doaj +1 more source
Coculture of TCR peptide-specific T cells with basic protein-specific T cells inhibits proliferation, IL-3 mRNA, and transfer of experimental autoimmune encephalomyelitis. [PDF]
, 1994 Halina Offner +5 more
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Neurogastroenterology &Motility, Volume 37, Issue 11, November 2025.Experimental study design. Mice were immunized with either α‐Lactalbumin or casein, and the resulting pathology of the enteric nervous system (ENS) was assessed using electron microscopy and immunofluorescence imaging. In vitro culture of isolated cells of the ENS was used to complement the in vivo findings.
Rittika Chunder +5 more
wiley +1 more source
EGFL7 reduces CNS inflammation in mouse
Nature Communications, 2018 Endothelial cells release extracellular matrix components that regulate inflammation. Here the authors demonstrate that the extracellular matrix component epidermal growth factor-like protein 7 regulates inflammation in experimental autoimmune ...
Catherine Larochelle +11 more
doaj +1 more source
Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats. [PDF]
, 1994 Evelyne Cash +5 more
openalex +1 more source