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Experimental Autoimmune Encephalomyelitis Influences GH-Axis in Female Rats. [PDF]
Zivkovic A +4 more
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Protective effect of TCR-mediated MAIT cell activation during experimental autoimmune encephalomyelitis. [PDF]
Walkenhorst M +14 more
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Experimental Autoimmune Encephalomyelitis in the Mouse
Current Protocols, 2021AbstractThis article details the materials and methods required for both active induction and adoptive transfer of experimental autoimmune encephalomyelitis (EAE) in the SJL mouse strain using intact proteins or peptides from the two major myelin proteins: proteolipid protein (PLP) and myelin basic protein (MBP).
Collin, Laaker +4 more
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Experimental Autoimmune Encephalomyelitis [PDF]
Much of our present understanding of the pathogenesis in multiple sclerosis (MS) and other disorders of the central nervous system (CNS) is based on information gained through studying experimental animal models. Whereas the investigation of human tissue samples—obtained by biopsies or postmortem—can provide only a focused view at one given time-point ...
Bernd C. Kieseier, Hans-Peter Hartung
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Microbiome Methods in Experimental Autoimmune Encephalomyelitis
Current Protocols, 2021AbstractMicrobiome composition studies are increasingly shedding light on animal models of disease. This paper describes a protocol for analyzing the gut microbiome composition prior to and after the induction of mice to experimental autoimmune encephalomyelitis (EAE), the principal animal model of the human neuroinflammatory demyelinating disease ...
David P, Daberkow +5 more
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Experimental Autoimmune Encephalomyelitis
2004Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system that is induced in laboratory animals by the generation of an immune response against myelin epitopes. It has been used as a prototype of Th1- and/or Th17-driven, organ-specific autoimmunity and as a model for the human disease ...
Benjamin M. Segal, Praveen Rao
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