Results 41 to 50 of about 1,306 (146)
Prevention of Experimental Autoimmune Uveoretinitis by Vasoactive IntestinalPeptide [PDF]
Archives of Ophthalmology, 2004 Vasoactive intestinal peptide (VIP), a neuropeptide that is known to be present in lymphoid tissue microenvironments, shows prominent anti-inflammatory actions.To examine the potential effect of VIP on the development of experimental autoimmune uveoretinitis (EAU).We immunized C57BL/6 mice with human interphotoreceptor retinoid-binding protein peptide ...
Hiroshi, Keino +5 more
openaire +2 more sources
Stem Cell Reports, 2017 Accumulating evidence shows that extracellular vesicles (EVs) produced by mesenchymal stem/stromal cells (MSCs) exert their therapeutic effects in several disease models.
Taeko Shigemoto-Kuroda +10 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 24, Issue 23, Page 13573-13588, December 2020., 2020 Abstract Autoreactive inflammatory CD4+ T cells, such as T helper (Th)1 and Th17 subtypes, have been found to associate with the pathogenesis of autoimmune disorders. On the other hand, CD4+ Foxp3+ T regulatory (Treg) cells are crucial for the immune tolerance and have a critical role in the suppression of the excessive immune and inflammatory response
Seyed‐Morteza Ehteshamfar +7 more
wiley +1 more source
The FASEB Journal, Volume 34, Issue 7, Page 9316-9336, July 2020., 2020 Abstract The lens and central cornea are avascular. It was assumed that the adult lens had no source of immune cells and that the basement membrane capsule surrounding the lens was a barrier to immune cell migration. Yet, microfibril‐associated protein‐1 (MAGP1)‐rich ciliary zonules that originate from the vasculature‐rich ciliary body and extend along
JodiRae DeDreu +6 more
wiley +1 more source
FEBS Open Bio, Volume 10, Issue 6, Page 969-978, June 2020., 2020 Autoimmune pancreatitis frequently causes acute episodes with clinical symptoms parallel to those of acute pancreatitis. Due to their significant immunomodulatory capabilities, mesenchymal stromal cells (MSCs) have been proposed as a novel treatment strategy for various immune and inflammatory pathologies including those with autoimmune origins.
Robbie R. Goodman, John E. Davies
wiley +1 more source
Macrophages and Uveitis in Experimental Animal Models
Mediators of Inflammation, 2015 Resident and infiltrated macrophages play relevant roles in uveitis as effectors of innate immunity and inductors of acquired immunity. They are major effectors of tissue damage in uveitis and are also considered to be potent antigen-presenting cells. In
Salvador Mérida +3 more
doaj +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 36, Issue 5, Page 363-370, May 2020., 2020 Abstract Recurrent pregnancy loss (RPL) is three or more times of consecutive spontaneous loss of pregnancy. The underlying cause is complicated and the etiology of over 50% of RPL patients is unclear. In the present study, bone marrow mesenchymal stem cells were isolated from CBA/J female mice and exosomes were isolated from cell culture medium by ...
Yan‐Jie Xiang +7 more
wiley +1 more source
Allergology International, 1999 The immunosuppressive effect of ethyl O-(N-(pcarboxyphenyl)-carbamoyl)-mycophenolate(CAM) was examined in interphotoreceptor retinoid-binding protein (IRBP)-induced experimental autoimmune uveoretinitis (EAU) in rats.
Jun-ichi Sakai +6 more
doaj +1 more source
Small heat shock protein αA-crystallin prevents photoreceptor degeneration in experimental autoimmune uveitis. [PDF]
PLoS ONE, 2012 The small heat shock protein, αA-crystallin null (αA-/-) mice are known to be more prone to retinal degeneration than the wild type mice in Experimental Autoimmune Uveoretinitis (EAU).
Narsing A Rao +3 more
doaj +1 more source