Results 51 to 60 of about 2,734 (194)

Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]

, 2010
Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M., Hamann, Jörg, Hoek, Robert M., Huitinga, Inge, Koning, Nathalie, Pouwels, Walter, Raes, Geert, van Eijk, Marco, Voehringer, David   +8 more
core   +1 more source

An immune response to the avascular lens following wounding of the cornea involves ciliary zonule fibrils

The FASEB Journal, Volume 34, Issue 7, Page 9316-9336, July 2020., 2020
Abstract The lens and central cornea are avascular. It was assumed that the adult lens had no source of immune cells and that the basement membrane capsule surrounding the lens was a barrier to immune cell migration. Yet, microfibril‐associated protein‐1 (MAGP1)‐rich ciliary zonules that originate from the vasculature‐rich ciliary body and extend along
JodiRae DeDreu, Caitlin J. Bowen, Caitlin M. Logan, Sonali Pal‐Ghosh, Paola Parlanti, Mary Ann Stepp, A. Sue Menko   +6 more
wiley   +1 more source

Mesenchymal stromal cells and their derivatives – putative therapeutics in the management of autoimmune pancreatitis

FEBS Open Bio, Volume 10, Issue 6, Page 969-978, June 2020., 2020
Autoimmune pancreatitis frequently causes acute episodes with clinical symptoms parallel to those of acute pancreatitis. Due to their significant immunomodulatory capabilities, mesenchymal stromal cells (MSCs) have been proposed as a novel treatment strategy for various immune and inflammatory pathologies including those with autoimmune origins.
Robbie R. Goodman, John E. Davies
wiley   +1 more source

Mesenchymal stem cells‐derived exosomes improve pregnancy outcome through inducing maternal tolerance to the allogeneic fetus in abortion‐prone mating mouse

The Kaohsiung Journal of Medical Sciences, Volume 36, Issue 5, Page 363-370, May 2020., 2020
Abstract Recurrent pregnancy loss (RPL) is three or more times of consecutive spontaneous loss of pregnancy. The underlying cause is complicated and the etiology of over 50% of RPL patients is unclear. In the present study, bone marrow mesenchymal stem cells were isolated from CBA/J female mice and exosomes were isolated from cell culture medium by ...
Yan‐Jie Xiang, Yan‐Yan Hou, Hong‐Li Yan, Hui Liu, Yan‐Xin Ge, Na Chen, Jian‐Feng Xiang, Cui‐Fang Hao   +7 more
wiley   +1 more source

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model [PDF]

, 2016
Endotoxin-induced uveitis (EIU) in rodents is a model of acute Toll-like receptor 4 (TLR4)-mediated organ inflammation, and has been used to model human anterior uveitis, examine leukocyte trafficking and test novel anti-inflammatory therapeutics.
Ali, Robin R, Chu, Colin J, Copland, David A, Dick, Andrew D, Gardner, Peter J, Gonzalez-Cordero, Anai, Kleine Holthaus, Sophia-Martha, Liyanage, Sidath E, Luhmann, Ulrich F O, Smith, Alexander J   +9 more
core   +7 more sources

Oral administration of antigen in the treatment of eye disease [PDF]

, 1997
Comment on the Oral administration of antigen in the treatment of eye ...
Williams, Keryn Anne
core   +1 more source

Rhodopsin-induced experimental autoimmune uveoretinitis in monkeys. [PDF]

British Journal of Ophthalmology, 1989
We present the first evidence that purified rhodopsin can induce experimental autoimmune uveoretinitis (EAU) in monkeys. Injection of a highly purified lipid-free rhodopsin preparation provokes severe chorioretinitis with concomitant anterior uveitis.
J J, Schalken, H J, Winkens, A H, Van Vugt, W J, De Grip, R M, Broekhuyse   +4 more
openaire   +2 more sources

CD4+CCR6+ T cells, but not γδ T cells, are important for the IL‐23R‐dependent progression of antigen‐induced inflammatory arthritis in mice

European Journal of Immunology, Volume 50, Issue 2, Page 245-255, February 2020., 2020
Abstract IL‐23 plays an important role in the development of arthritis and the IL‐23 receptor (IL‐23R) is expressed on different types of T cells. However, it is not fully clear which IL‐23R+ T cells are critical in driving T cell‐mediated synovitis. We demonstrate, using knock‐in IL‐23R‐GFP reporter (IL‐23RGFP/+) mice, that CD4+CCR6+ T cells and γδ T 
Wida Razawy, Patrick S. Asmawidjaja, Anne‐Marie Mus, Nazike Salioska, Nadine Davelaar, Nicole Kops, Mohamed Oukka, C. Henrique Alves, Erik Lubberts   +8 more
wiley   +1 more source

Macrophages and Uveitis in Experimental Animal Models

Mediators of Inflammation, 2015
Resident and infiltrated macrophages play relevant roles in uveitis as effectors of innate immunity and inductors of acquired immunity. They are major effectors of tissue damage in uveitis and are also considered to be potent antigen-presenting cells. In
Salvador Mérida, Elena Palacios, Amparo Navea, Francisco Bosch-Morell   +3 more
doaj   +1 more source

Autoimmunity, Autoinflammation, and Infection in Uveitis [PDF]

, 2018
Funding/Support: No funding or grant support. Financial Disclosures: John V. Forrester has received an honorarium for lecturing from Janssen (London, UK). Lucia Kuffova has undertaken consultancy work for Abbvie (London, UK). Andrew D.
Dick, Andrew D., Forrester, John V., Kuffova, Lucia   +2 more
core   +4 more sources