Results 61 to 70 of about 434,787 (260)

Tauopathy and cognitive impairment in experimental diabetes mellitus

Сахарный диабет, 2017
Currently, diabetes mellitus (DM) is the most common metabolic disorder, which is manifested by hyperglycemia and leads to vascular and cognitive impairment. Mechanisms of cognitive dysfunction in patients with DM remain highly unclear, thus complicating
Mariia V. Matveeva, Yulia G. SamoiIova, Natalia G. Zhukova, Oksana A. Oleynik, Maria A. Rotkank   +4 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

OXIDATIVE STRESS CARACTERIZATION IN STREPTOZOTOCIN-DIABETIC WISTAR RATS

Vitae, 2009
Diabetes is a chronic metabolic disease. Numerous studies have demonstrated that diabetes mellitus is associated to free radicals increase derived from oxygen and to the organism potential antioxidant decrease generating oxidative damage of some cell ...
Ángela C. MORA H., Diana M. ARAGÓN N., Luis F. OSPINA G.   +2 more
doaj  

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Determining Effects of Leg Exercises to Increase Blood Circulation in The Feet of Diabetes Mellitus Patients

Indonesian Contemporary Nursing Journal, 2018
Introduction: Based on the routine surveillance of non-communicable diseases (NCDs) hospital based in South Sulawesi diabetes mellitus highest cause of death in the amount of 41.56%.
Hasnah Hasnah, Ambo Sau
doaj   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

Pengaruh Modifikasi Senam Kaki dan Terapi Kelereng terhadap Kadar Glukosa Darah Penderita Diabetes Melitus

Journal of Health (JOH)
Introduction: Diabetes mellitus is a metabolic disease characterized by increased blood glucose levels that occur due to insulin disorders. One of the non-pharmacological treatments that can be taken is by providing modified foot exercise therapy and ...
Wita Pamelia, Frengki Apryanto, Wira Daramatasia   +2 more
doaj   +1 more source

Effect of induced gestational diabetes on TBX20 gene expression in the heart of the 11.5-day-old embryo of the C57BL/6 mouse

مجله دانشگاه علوم پزشکی گرگان, 2021
Background and Objective: Diabetes mellitus is one of the most common metabolic and global health threats. The gene needed for the development of the TBX20 gene is the fusion of the gene, and the defect in the sequence and expression of this gene also ...
Zeynab Alinezhad, Masoud Golalipour, Mohammad Jafar Golalipour   +2 more
doaj  

THE ROLE OF NITROGEN OXIDE AND NITROSATIVE STRESS IN BURN WOUND HEALING IN DIABETES MELLITUS

Медична наука України, 2019
Relevance. The risk of developing of diabetic foot ulcers is 25% over the lifetime of patients with diabetes mellitus. Inhibition of wound healing is associated with impaired macrophage polarization, decreased bioavailability of growth factors, enhanced ...
O.I. Myronenko, L.V. Natrus, T.I. Panova
doaj   +1 more source