Results 91 to 100 of about 1,042,213 (319)

The natural history of trachoma infection and disease in a Gambian cohort with frequent follow-up. [PDF]

, 2008
BACKGROUND: The natural history of ocular Chlamydia trachomatis infections in endemic communities has not been well characterised and is an important determinant of the effectiveness of different mass treatment strategies to prevent blindness due to ...
Nicholas C Grassly, Michael E Ward, Ferris, Shirley, Shirley Ferris, Grassly, Nicholas C, Ferris Shirley, Mabey David C., Robin L Bailey, Bailey, Robin L, Ward, Michael E, Bailey Robin L., Mabey, David C, David C Mabey, Grassly Nicholas C., Ward Michael E.   +14 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signaling.

, 2011
The outcome of infection depends on multiple layers of immune regulation, with innate immunity playing a decisive role in shaping protection or pathogenic sequelae of acquired immunity.
Jan Burgold, Hafalla, J.C., Kai Matuschewski, Julius Clemence R. Hafalla, Gross, Olaf, Jürgen Ruland, Stefan H. E. Kaufmann, Kaufmann, Stefan H. E., Olaf Gross, Hafalla, Julius Clemence R., Gross, O., Matuschewski, K., Matuschewski, Kai, Ruland, Jürgen, Kaufmann, Stefan HE, Ruland, J., Burgold, Jan, Hafalla, Julius Clemence R, Dorhoi, Anca, Burgold, J., Anca Dorhoi, Dorhoi, A., Kaufmann, S.H.   +22 more
core   +1 more source

The Role of Innate APOBEC3G and Adaptive AID Immune Responses in HLA-HIV/SIV Immunized SHIV Infected Macaques [PDF]

, 2012
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Wang, Yufei, Singh Mahavir, Schøller, Jørgen, David Montefiori, Bunnik, Evelien M, Montefiori, D, Vaughan Robert, Mahavir Singh, Jørgen Schøller, Singh, Mahavir, Bergmeier, LA, Whittall, T, Thomas Lehner (171103), Rahman Durdana, Mahavir Singh (70735), Durdana Rahman (171080), Scholler, J, Vaughan, Robert, Rahman, D, Vaughan, R, Singh, M, Whittall Trevor, Bunnik Evelien M., Robert Vaughan, Thomas Lehner, Lesley A. Bergmeier (171089), Rahman, Durdana, Montefiori, David, Yufei Wang (171069), Evelien M. Bunnik (125512), Bergmeier, Lesley A., Whittall, Trevor, Lehner, T, Schøller Jørgen, Lehner Thomas, Hanneke Schuitemaker, Yufei Wang, Bergmeier, Lesley A, Lehner, Thomas, Lesley A Bergmeier, Schuitemaker, Hanneke, Montefiori David, Schuitemaker, H, Schuitemaker Hanneke, Bunnik, Evelien M., Trevor Whittall (171074), Trevor Whittall, Hanneke Schuitemaker (85702), David Montefiori (161606), Wang, Y, Robert Vaughan (5968), Jørgen Schøller (143988), Wang Yufei, Bergmeier Lesley A., Durdana Rahman, Bunnik, EM, Evelien M Bunnik   +56 more
core   +1 more source

Single-cell analysis of mature hepatocytes reveals an IRF1-driven restriction of HDV infection

JHEP Reports
Background & Aims: Stem cell-derived hepatocyte-like cells (HLCs) are an in vitro model of hepatocytes reproducing mature hepatic functions. However, heterogeneous or imperfect differentiation may limit their biological relevance.
Frauke Lange, Jonathan Garn, Matthias Bruhn, Thomas Pietschmann, Arnaud Carpentier   +4 more
doaj   +1 more source

Incorporation of Hepatitis C Virus E1 and E2 Glycoproteins: The Keystones on a Peculiar Virion

Viruses, 2014
Hepatitis C virus (HCV) encodes two envelope glycoproteins, E1 and E2. Their structure and mode of fusion remain unknown, and so does the virion architecture.
Gabrielle Vieyres, Jean Dubuisson, Thomas Pietschmann   +2 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain.

, 2012
It is well established that IFN-γ is required for the development of experimental cerebral malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the temporal and tissue-specific cellular sources of IFN-γ during P.
Hunter, Christopher A, Couper, Kevin N, Riley, Eleanor M, Greig, Rachel, Blount, Daniel G, Blount, Daniel G., Stumhofer, Jason S, Hafalla, Julius CR, De Souza, J. Brian, Findlay, Emily Gwyer, Shaw, Tovah N, de Souza, J Brian, Riley, Eleanor M., Shaw, Tovah N., Stumhofer, Jason S., Hunter, Christopher A., Hafalla, Julius C R, Couper, Kevin N., Gwyer Findlay, Emily, Villegas-Mendez, Ana   +19 more
core   +1 more source