Results 111 to 120 of about 15,762 (228)

MicroRNA‐Mediated Placental Maladaptation in Preeclampsia Pathogenesis

open access: yesFASEB BioAdvances, Volume 8, Issue 9, September 2026.
Graphical representation of miRNA‐mediated placental maladaptation in preeclampsia. Under normal pregnancy conditions, balanced expression of beneficial miRNAs (miR‐126‐3p, miR‐18a/b‐5p, miR‐144‐3p, miR‐378a‐5p, and miR‐146a‐5p) promotes trophoblast proliferation, migration and invasion, spiral artery remodeling, angiogenesis, mitochondrial function ...
Sarbani Saha, Rupasri Ain
wiley   +1 more source

The role of exportin 6 in cytoskeletal-mediated cell death and cell adhesion in human non-small-cell lung carcinoma cells following doxorubicin treatment [PDF]

open access: yes, 2014
The actin cytoskeleton plays an important role in various cellular processes. The different forms ofactin (G-actin and F-actin) participate in the organization of nuclear structure and its functions.
Gagat, Maciej; Katedra i Zakład Histologii i Embriologii Collegium Medicum Uniwersytetu Mikołaja Kopernika   +4 more
core   +1 more source

sj-docx-5-tct-10.1177_15330338211039132 - Supplemental material for Exportin-T: A Novel Prognostic Predictor and Potential Therapeutic Target for Neuroblastoma

open access: yes, 2021
Supplemental material, sj-docx-5-tct-10.1177_15330338211039132 for Exportin-T: A Novel Prognostic Predictor and Potential Therapeutic Target for Neuroblastoma by Li-Jia Pan, Jian-Lei Chen, Zhi-Xiang Wu and Ye-Ming Wu in Technology in Cancer Research ...
Li-Jia Pan (11377147)   +3 more
core   +1 more source

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

open access: yesThe FEBS Journal, Volume 293, Issue 17, Page 5121-5139, September 2026.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture   +3 more
wiley   +1 more source

Melphalan and exportin 1 inhibitors exert synergistic anti-tumor effects in preclinical models of human multiple myeloma

open access: yesCancer Research, 2020
Inhibition of exportin 1 with selinexor synergistically sensitizes human multiple myeloma to melphalan by inhibiting Fanconi anemia pathway-mediated DNA repair.
J. Turner   +9 more
semanticscholar   +1 more source

Hypoxia‐inducible factor‐1a (HIF1a) as a context‐dependent integrator of metabolic stress in skeletal muscle

open access: yesThe Journal of Physiology, Volume 604, Issue 18, Page 7539-7558, 15 September 2026.
Abstract figure legend Hypoxia‐inducible factor‐1a (HIF1a) integrates physiological and pathological inputs in skeletal muscle, including exercise, circadian timing, cytotoxins and disease. These inputs alter mitochondrial oxidative function, redox state, reactive oxygen species, and local oxygen availability, leading to intermittent or sustained HIF1a
Nicole Welch   +6 more
wiley   +1 more source

Parental experiences orchestrate locust egg hatching synchrony by regulating nuclear export of precursor miRNA

open access: yesNature Communications
Parental experiences can affect the phenotypic plasticity of offspring. In locusts, the population density that adults experience regulates the number and hatching synchrony of their eggs, contributing to locust outbreaks.
Ya′nan Zhu   +6 more
doaj   +1 more source

An Exportin-1–dependent microRNA biogenesis pathway during human cell quiescence

open access: yes, 2017
Significance Quiescence is a growth-arrested cellular state; genes involved in this process are finely regulated by several factors, including miRNAs.
Ivan Martinez   +8 more
core   +1 more source

Cold-induced FOXO1 nuclear transport aids cold survival and tissue storage

open access: yesNature Communications
Cold-induced injuries severely limit opportunities and outcomes of hypothermic therapies and organ preservation, calling for better understanding of cold adaptation.
Xiaomei Zhang   +22 more
doaj   +1 more source

Prognostic significance of exportin-5 in hepatocellular carcinoma

open access: yesWorld Journal of Gastrointestinal Oncology
BACKGROUND Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. As liver cancer often presents no noticeable symptoms in its early stages, most patients are diagnosed at an advanced stage, complicating treatment.
Li, Hao   +3 more
openaire   +2 more sources

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