Results 71 to 80 of about 29,704,271 (175)
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Immunology &Cell Biology, EarlyView.Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
, 2018 The effect of deregulation of nuclear export mediated by exportin-1, with consequent cellular mislocalization of p33ING1b, a member of the tumor suppressor gene family, has not been previously investigated in head and neck squamous cell cancer (HNSCC ...
Ozdas, Sibel, Sibel í–zdaş
core +1 more source
Physiological Reports, 2023 Cold water immersion (CWI) following intense exercise is a common athletic recovery practice. However, CWI impacts muscle adaptations to exercise training, with attenuated muscle hypertrophy and increased angiogenesis.
Randall F. D'Souza +10 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, Volume 7, Issue 3, Page 109-124, September 2026.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
How Epitranscriptomic Machinery Senses Environmental Cues
Advanced Biology, Volume 10, Issue 9, September 2026.Exogenous exposures, microenvironmental signals, and intracellular metabolic or redox states can alter RNA‐modification machinery through catalytic chemistry, signaling‐dependent PTMs, compartmental redistribution, or changes in abundance and composition.
Shayan Jalali, Ehsan Pashay Ahi
wiley +1 more source
Exportin-5 orthologues are functionally divergent among species
, 2006 Exportin-5, an evolutionarily conserved nuclear export factor belonging to the importin-b family of proteins, is known to play a role in the nuclear export of small noncoding RNAs such as precursors of microRNA, viral minihelix RNA and a subset of tRNAs ...
Yoshihiro Yoneda +6 more
core +1 more source
Exportin-5 mediates nuclear export of minihelix-containing RNAs
, 2003 International audienceThe adenovirus VA1 RNA (VA1.), a 160-nucleotide (nt)- long RNA transcribed by RNA polymerase III, is efficiently exported from the nucleus to the cytoplasm of infected cells, where it antagonizes the interferon-induced antiviral ...
Alain Doglio +13 more
core +2 more sources
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.Resistance to venetoclax has become a critical bottleneck limiting its long‐term clinical benefits. A thorough understanding of the underlying resistance mechanisms and the development of novel strategies to overcome resistance are central to improving survival outcomes in elderly AML patients. Abstract To date, the treatment of acute myeloid leukaemia
Jinlin Zhang +8 more
wiley +1 more source
Exportin T and Exportin 5: tRNA and miRNA biogenesis - and beyond
, 2012 The biogenesis of most eukaryotic kinds of RNA requires nuclear export, which is mediated by a variety of specific nuclear transport receptors. The nuclear export receptors Exportin-t (Exp-t) and Exportin 5 (Exp5), and their homologues, are involved in ...
Martin, Roman +3 more
core +1 more source
BMC Cancer, 2018 Background Small intestinal neuroendocrine tumors (SI-NETs) originate from enterochromaffin cells scattered in the intestinal mucosa of the ileum and jejunum.
Elham Barazeghi +5 more
doaj +1 more source