Results 121 to 130 of about 2,321,627 (280)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Assessing the utility of gene co-expression stability in combination with correlation in the analysis of protein-protein interaction networks

BMC Genomics, 2011
Background Gene co-expression, in the form of a correlation coefficient, has been valuable in the analysis, classification and prediction of protein-protein interactions.
Patil Ashwini, Nakai Kenta, Kinoshita Kengo   +2 more
doaj   +1 more source

Validating internal controls for quantitative plant gene expression studies

BMC Plant Biology, 2004
Background Real-time reverse transcription PCR (RT-PCR) has greatly improved the ease and sensitivity of quantitative gene expression studies. However, accurate measurement of gene expression with this method relies on the choice of a valid reference for
Brunner Amy M, Yakovlev Igor A, Strauss Steven H   +2 more
doaj   +1 more source

Reference genes expression stability in Avena sativa L. during compatible and incompatible interactions with Puccinia graminis. [PDF]

Sci Rep, 2022
Sowa S, Sozoniuk M, Toporowska J, Kowalczyk K, Paczos-Grzęda E.   +4 more
europepmc   +1 more source

EXPRESSION AND STABILITY OF THE MARBLED ALLELE IN MAIZE [PDF]

Genetics, 1961
HE pigment-producing action of the R' allele (colored aleurone, red seedling) in maize regularly is reduced among the off spring of heterozygotes carrying an allele, RSt, conditioning stippled aleurone and green seedling (BRINK 1956). The modified forms of R' which arise through such intrachromosomal changes at or near the R locus are heritable ...
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains

The EMBO Journal
The centromeric histone H3 variant CENP-A is overexpressed in many cancers. The mislocalization of CENP-A to noncentromeric regions contributes to chromosomal instability (CIN), a hallmark of cancer.
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Subhash Chandra Sethi, Lu Chen, Samantha Sevilla, Natasha J Caplen, Raj Chari, Tatiana S Karpova, Katherine McKinnon, Matthew AM Todd, Vishal Koparde, Ken Chih-Chien Cheng, Michael L Nielsen, Anja Groth, Munira A Basrai   +17 more
doaj   +1 more source

Reference gene expression stability within the rat brain under mild intermittent ketosis induced by supplementation with medium-chain triglycerides. [PDF]

PLoS One, 2023
Schwarz AP, Nikitina VA, Krytskaya DU, Shcherbakova KP, Trofimov AN.   +4 more
europepmc   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Design of a fractional control using performance contours. Application to an electromechanical system [PDF]

, 2003
The article proposes a frequency-based method to design a controller ensuring dynamic behavior of a closed-loop control: the first overshoot of the step response in the tracking mode or in the regulation mode, the damping ratio and the natural frequency ...
Lanusse, Patrick, Oustaloup, Alain, Pommier-Budinger, Valérie   +2 more
core   +1 more source