Results 111 to 120 of about 6,818,443 (298)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

CYR61 (CCN1) protein expression during fracture healing in an ovine tibial model and its relation to the mechanical fixation stability

, 2006
The formation of new blood vessels is a prerequisite for bone healing. CYR61 (CCN1), an extracellular matrix-associated signaling protein, is a potent stimulator of angiogenesis and mesenchymal stem cell expansion and differentiation.
Epari, Devakara, Schutze, Norbert, Jakob, Franz, Duda, Georg, Schell, Hanna, Lienau, Jasmine, Bail, Hermann   +6 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Expression stability ranking of the 9 candidate genes.

, 2016
Expression stability ranking of the 9 candidate genes.
Yuhu Zuo (3590174), Lihua Yin (807774), Dong Han (199240), Xiwang Ke (2575816), Chao Chi (3590171), Yongqiang Shen (1306521)   +5 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Expression stability ranking of the 11 candidate reference genes.

, 2017
Expression stability ranking of the 11 candidate reference genes.
Xiang Zhang (19800), Xiaochun Liu (1829419), Shaoxiong Ding (154166), Huan Wang (109286), Qiaohong Liu (3738520)   +4 more
core   +1 more source

Artificial environments for the co-translational stabilization of cell-free expressed proteins [PDF]

, 2013
An approach for designing individual expression environments that reduce or prevent protein aggregation and precipitation is described. Inefficient folding of difficult proteins in unfavorable translation environments can cause significant losses of ...
Volker Dötsch, Dötsch, Volker, Frank Bernhard, Kai, Lei, Kaldenhoff, Ralf, Lei, Kai, Lei Kai, Ralf Kaldenhoff, Bernhard, Frank, Kaldenhoff Ralf, Dötsch Volker, Kai Lei, Bernhard Frank   +12 more
core   +2 more sources

Taste expression and stability of L-theanine in strong-flavor Baijiu [PDF]

Zhongguo niangzao
In this study, applying electronic tongue detection combined with sensory evaluation, the taste expression was analyzed by adding L-theanine 0, 0.04%, 0.06%, 0.08%, 0.10%, 0.16%, and 1.00%, respectively to strong-flavor (Nongxiangxing) Baijiu with ...
CAO Xiaonian, LV Yangjun, LIU Qingqing, ZHU Yuejin, CAO Tianchi, LAN Yu, SHEN Caihong, ZHANG Shikang
doaj   +1 more source

Stability, Expressivity, and Spectra

We develop a theorem-based synthesis connecting nonlinear approximation, gradient-flow reachability, power-law spectral learning, compute-optimal training, and transformer attention. First, we sharpen the stability–expressivity interpretation of the deep ReLU approximation phase diagram: the fast phase uses growing depth and discontinuous target-to ...
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source