Results 91 to 100 of about 6,818,443 (298)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Plants(1) Reverse transcription quantitative real-time PCR (RT-qPCR) requires reliable reference genes for accurate data normalization; however, optimal reference genes for the economically and ecologically valuable timber species Phoebe zhennan remain ...
Beibei Chen +5 more
doaj +1 more source
CE-Prompt: enhance prompt expression stability by multiple understanding [PDF]
PeerJ Computer ScienceIn this article, we propose CE-Prompt, an enhanced version of Prompt-Tuning designed to address issues such as the instability of random initialization and inefficiencies caused by long text in pre-trained large language models (LLMs).
Wujian Yang +3 more
doaj +2 more sources
Thrombospondin expression in myofibers stabilizes muscle membranes
eLife, 2016 Skeletal muscle is highly sensitive to mutations in genes that participate in membrane stability and cellular attachment, which often leads to muscular dystrophy. Here we show that Thrombospondin-4 (Thbs4) regulates skeletal muscle integrity and its susceptibility to muscular dystrophy through organization of membrane attachment complexes.
Davy Vanhoutte +13 more
openaire +3 more sources
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Evaluation of reference genes for gene expression studies in pig muscle tissue by real-time PCR
Czech Journal of Animal Science, 2011 The selection of reference genes is essential for gene expression studies when using a real-time quantitative polymerase chain reaction (PCR). Reference gene selection should be performed for each experiment because the gene expression level may be ...
M. Nesvadbová, A. Knoll
doaj +1 more source
An algorithm to analyze stability of gene-expression patterns
Discrete Applied Mathematics, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jutta Gebert +4 more
openaire +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Expression stability analysis of the reference genes by BestKeeper.
, 2013 Expression stability analysis of the reference genes by BestKeeper.
Sang-Je Park (282182) +10 more
core +2 more sources
NeuronSeek: On Stability and Expressivity of Task-Driven Neurons
Drawing inspiration from our human brain that designs different neurons for different tasks, recent advances in deep learning have explored modifying a network's neurons to develop so-called task-driven neurons. Prototyping task-driven neurons (referred to as NeuronSeek) employs symbolic regression (SR) to discover the optimal neuron formulation and ...
Hanyu Pei +6 more
openaire +3 more sources