Results 131 to 140 of about 6,818,443 (298)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Enhancing the accuracy of qPCR normalization in Bactrocera zonata: A systematic study for the selection of condition-optimized reference genes for gene expression studies

open access: yesScientific Reports
Bactrocera zonata (Diptera: Tephritidae) is a highly destructive polyphagous pest that infests a wide range of economically important fruit crops. Understanding its growth, development, reproduction, and responses to environmental stresses is essential ...
T. C Suman   +7 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Expression stability values for bamboo candidate reference genes calculated using Normfinder.

open access: yes, 2013
Note: Expression stability and ranking of 14 candidate reference genes calculated with NormFinder in all samples, plant tissues and developmental stages. Lower average expression stability (M value) indicates more stable expression.
Xiaotie Li (378522)   +5 more
core   +1 more source

Assessing the utility of gene co-expression stability in combination with correlation in the analysis of protein-protein interaction networks

open access: yesBMC Genomics, 2011
Background Gene co-expression, in the form of a correlation coefficient, has been valuable in the analysis, classification and prediction of protein-protein interactions.
Patil Ashwini   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Expression stability of 12 candidate reference genes calculated by RefFinder.

open access: yes, 2018
Expression stability of 12 candidate reference genes calculated by RefFinder.
Lei Li (29537)   +4 more
core   +1 more source

DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains

open access: yesThe EMBO Journal
The centromeric histone H3 variant CENP-A is overexpressed in many cancers. The mislocalization of CENP-A to noncentromeric regions contributes to chromosomal instability (CIN), a hallmark of cancer.
Vinutha Balachandra   +17 more
doaj   +1 more source

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