Extended Infusion of Meropenem in Neonatal Sepsis: A Historical Cohort Study [PDF]
Antibiotics, 2022 This single-center historical cohort study investigated the effectiveness and safety of extended infusion (EI) compared with short-term infusion (STI) of meropenem in neonatal sepsis.
Guangna Cao +5 more
doaj +7 more sources
Development of the Extended Infusion Set and Its Mechanism of Action [PDF]
Journal of Diabetes Science and Technology, 2022 Continuous subcutaneous insulin infusion (CSII, or insulin pump) and continuous glucose monitoring (CGM) sensors have been increasingly used and associated with improved glycemic control by people with type 1 diabetes and insulin-requiring type 2 diabetes. Commonly used infusion sets in most CSII systems are limited to a wear time of 3 days.
Ohad Cohen +2 more
exaly +4 more sources
Extended infusion versus intermittent infusion of imipenem in the treatment of ventilator-associated pneumonia [PDF]
Drug Design, Development and Therapy, 2017 Mohamed M Ibrahim,1 Tarek Fouad Tammam,2 Mohy El Deen Ebaed,3 Hatem A Sarhan,4 Gamal F Gad,5 Amal K Hussein4 1Department of Clinical Pharmacy, Faculty of Pharmacy, Minia University, Minia, Egypt; 2Department of Anesthesia and Intensive Care, Faculty of ...
Ibrahim MM +5 more
doaj +7 more sources
Impact of extended-infusion piperacillin-tazobactam in a Canadian community hospital [PDF]
Infectious Medicine, 2023 Background: Studies have demonstrated improved clinical outcomes with extended infusion (EI) piperacillin/tazobactam (TZP) compared to standard infusion (SI). However, there is less evidence on its benefits in noncritically-ill patients. Hospital-wide EI
April J. Chan +8 more
doaj +4 more sources
Pharmacokinetics of imipenem in critically ill patients: Continuous infusion versus extended infusion in a real-world study [PDF]
Journal of International Medical ResearchObjective This study compared the pharmacokinetic/pharmacodynamic properties of extended infusion and continuous infusion of imipenem at equivalent daily doses in a real-world setting.
Ruixia Zhang, Yi Qin, Yayao Lv, Yi Zhang
doaj +4 more sources
Meropenem: continuous or extended infusion? [PDF]
Critical Care, 2020 Frédéric Frippiat +2 more
doaj +5 more sources
Clinical outcomes of prolonged infusion (extended infusion or continuous infusion) versus intermittent bolus of meropenem in severe infection: A meta-analysis. [PDF]
PLoS ONE, 2018 BACKGROUND:Meropenem exhibits time-dependent antimicrobial activity and prolonged infusion (PI) (extended infusion or continuous infusion, EI or CI) of meropenem can better achieve pharmacodynamics target when comparing with intermittent bolus (IB ...
Zhenwei Yu +4 more
doaj +5 more sources
Cefepime extended infusion versus intermittent infusion: Clinical and cost evaluation
Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Background: Extended infusion cefepime (1 gram every 6 hours administered over 3 hours) achieves pharmacodynamic efficacy against bacteria with a MIC of ≤8 mg/L in Monte Carlo simulations.
Aalok V. Khole +3 more
doaj +4 more sources
Extended infusion of piperacillin–tazobactam versus intermittent infusion in critically ill egyptian patients: a cost-effectiveness study [PDF]
Scientific Reports, 2022 Extended infusion of piperacillin/tazobactam over 4 h has been proposed as an alternate mode of administration to the 30-min intermittent infusion to optimize treatment effects in patients with gram-negative bacterial infections.
Christina Medhat Naiim +3 more
doaj +2 more sources
Extended infusion of β-lactams significantly reduces mortality and enhances microbiological eradication in paediatric patients: a systematic review and meta-analysisResearch in context [PDF]
EClinicalMedicine, 2023 Summary: Background: Paediatric patients are often exposed to subtherapeutic levels or treatment failure of β-lactams, and prolonged infusion may be beneficial.
Kinga Anna Budai +10 more
doaj +2 more sources