Extended Infusion of Piperacillin/Tazobactam in Children. [PDF]
J Pediatr Pharmacol Ther, 2017 OBJECTIVES Extended-infusion piperacillin/tazobactam (TZP) has been associated with positive clinical outcomes in adults, but similar data in children are lacking. The objective of this study was to describe efficacy outcomes with pediatric patients receiving extended-infusion TZP. METHODS This
Knoderer CA +3 more
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Clinical Challenge: Standard Versus Extended Meropenem Infusion in Children
Turkish Archives of PediatricsThe management of Gram-negative bacterial infections poses a significant challenge due to the emergence of highly effective antibiotic-resistant mechanisms, leading to treatment failures, particularly among hospitalized children.
Ahmet Erhan Kişi +2 more
doaj +5 more sources
Antibiotics, 2023 This systematic review aimed to compare extended infusion or continuous infusion with bolus infusion for febrile neutropenia (FN). We included clinical trials comparing extended or continuous infusion with bolus infusion of beta-lactam antibiotics as ...
Kazuhiro Ishikawa +5 more
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A Retrospective Analysis of Intravenous Push versus Extended Infusion Meropenem in Critically Ill Patients [PDF]
AntibioticsMeropenem is a broad-spectrum antibiotic used for the treatment of multi-drug-resistant infections. Due to its pharmacokinetic profile, meropenem’s activity is optimized by maintaining a specific time the serum concentration remains above the minimum ...
Emory G. Johnson +7 more
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Antibiotics, 2023 The efficacy of extended meropenem infusions in patients with nosocomial pneumonia is not well defined. Therefore, we compared the clinical outcomes of extended versus intermittent meropenem infusions in the treatment of nosocomial pneumonia.
Dong-gon Hyun +7 more
doaj +2 more sources
International Journal of Infectious Diseases, 2020 Objectives: Alternative dosing strategies for β-lactams – the most common antibiotics used to treat critically ill patients with respiratory tract infections – have been recommended to maximize the duration of exposure and reduce drug resistance.
Laila Aboulatta +4 more
doaj +3 more sources
Extended Infusion of Beta-Lactams and Glycopeptides: A New Era in Pediatric Care? A Systematic Review and Meta-Analysis [PDF]
AntibioticsOptimizing antibiotic therapy is imperative with rising bacterial resistance and high infection mortality. Extended infusion defined as a continuous infusion (COI) or prolonged infusion (PI) of beta-lactams and glycopeptides might improve efficacy and ...
Andrea Rahel Burch +3 more
doaj +2 more sources
Compatibility and stability of seven selected cephalosporin antibiotics during extended infusion [PDF]
Science ProgressObjective To investigate the physical and chemical stability of cefminox sodium, cefuroxime sodium, cefoxitin sodium, ceftizoxime sodium, cefmetazole sodium, ceftazidime and cefamandole nafate when continuously infused with 0.9% sodium chloride (NS) and ...
Liting Zhang +5 more
doaj +2 more sources
Effect of extended infusion of meropenem and nebulized amikacin on Gram-negative multidrug-resistant ventilator-associated pneumonia [PDF]
Saudi Journal of Anaesthesia, 2018 Background: Ventilator-associated pneumonia (VAP) due to multidrug-resistant organisms (MDROs) is associated with a significant mortality in the Intensive Care Unit (ICU).
Mona Ahmed Ammar, Waleed Abdalla
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Extended vs Intermittent Infusion of Meropenem with Colistimethate Sodium and Risk of Acute Kidney Injury in Critically Ill Patients: A Propensity Score-Matched Retrospective Cohort Study [PDF]
Infection and Drug ResistanceQiaoqiao Hu,1 Huajun Wang2 1Department of Pharmacy, The Affiliated People’s Hospital of Ningbo University, Ningbo City, Zhejiang Province, 315000, People’s Republic of China; 2Department of Intensive Care Unit, The Affiliated People’s Hospital of Ningbo ...
Hu Q, Wang H
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