Results 21 to 30 of about 1,653,621 (270)

Continuous epidural infusion of morphine versus single epidural injection of extended-release morphine for postoperative pain control after arthroplasty: a retrospective analysis

Therapeutics and Clinical Risk Management, 2010
Stephanie Vanterpool, Randall Coombs, Karamarie FechoDepartment of Anesthesiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USABackground: This study retrospectively compared the continuous epidural infusion of ...
Stephanie Vanterpool, Randall Coombs, Karamarie Fecho   +2 more
doaj   +1 more source

Rationality of Time-Dependent Antimicrobial Use in Intensive Care Units in China: A Nationwide Cross-Sectional Survey

Frontiers in Medicine, 2021
Background: Extended/continuous infusion and therapeutic drug monitoring (TDM) of time-dependent antimicrobials are recommended for optimizing drug exposure for patients in intensive care units (ICUs), although practical application of these measures ...
Jiao Liu, Jiao Liu, Sheng Zhang, Sisi Huang, Yizhu Chen, Lidi Zhang, Hangxiang Du, Tao Wang, Yongan Liu, Yan Xu, Dechang Chen, Dechang Chen   +11 more
doaj   +1 more source

The OBTAINS study: A nationwide cross-sectional survey on the implementation of extended or continuous infusion of β-lactams and vancomycin among neonatal sepsis patients in China

Frontiers in Pharmacology, 2022
Background: Dosing strategies of β-lactams and vancomycin should be optimized according to pharmacokinetic/pharmacodynamic principles. However, there is no available data indicating the implementation of extended infusion (EI) or continuous infusion (CI)
Pengxiang Zhou, Pengxiang Zhou, Pengxiang Zhou, Pengxiang Zhou, Yinchu Cheng, Yinchu Cheng, Guangna Cao, Yan Xing, Suodi Zhai, Suodi Zhai, Xiaomei Tong, Kehu Yang, Kehu Yang   +12 more
doaj   +1 more source

Extended Duration Infusion of Hydroxocobalamin for Vasoplegic Rescue in Septic Shock [PDF]

Cureus, 2021
Nitric oxide (NO) is a gaseous signaling molecule and a key endogenous mediator of vascular tone. Hydroxocobalamin (HCB) affects NO-mediated vasoplegia as (1) a direct inhibitor of nitric oxide synthase (NOS), thereby decreasing its production, and (2) by binding directly to NO and acting as a scavenger.
Gerdes, Harrison J, Seelhammer, Troy G, Nei, Scott, Diaz Soto, Juan, Nabzdyk, Christoph G   +4 more
openaire   +2 more sources

Extended stability study of an extemporaneously analgesic solution of clonidine, ropivacaine and fentanyl

Brazilian Journal of Pharmaceutical Sciences, 2023
The aim of this work was to perform an extended stability study for the analgesic containing fentanyl, clonidine and ropivacaine in physiological saline solution 0.9% at different infusion sites, such as infusion bags, epidural infusion sets and syringes.
Alessandra Moreira de Oliveira, Jose Carlos Saraiva Gonçalves, Rita de Cássia Elias Estrela   +2 more
doaj   +1 more source

Extended infusion of cephalosporins, penicillins and carbapenems: a cost-effective point-of-view and critical appraisal of Surviving Sepsis Campaign guidelines

Journal of Evidence-Based Healthcare, 2022
Narrative/ introduction. In the last edition of the Surviving Sepsis Campaign guidelines - SSC guidelines -   recommendations regarding the optimization of antibiotics pharmacokinetics and pharmacodynamics (PK/PD) were made.
Sérgio Renato da Rosa Decker, Lucas Emanuel Marzzani, Pedro Rotta de Ferreira   +2 more
doaj   +1 more source

Evaluation of Implementation of Extended-Infusion Piperacillin-Tazobactam at an Academic Medical Center

, 2011
Class of 2011 AbstractOBJECTIVES: The objective of this study was to compare patient clinical outcomes, vascular access line administration complications, and piperacillin-tazobactam costs before and after implementation of an extended infusion ...
DiPede, Michael, Radosevich, John, Brunelle, Adam   +2 more
core   +5 more sources

Extended-Infusion versus Standard-Infusion Piperacillin-Tazobactam for Sepsis Syndromes at a Tertiary Medical Center [PDF]

Antimicrobial Agents and Chemotherapy, 2014
ABSTRACT Piperacillin-tazobactam (PTZ) is frequently used as empirical and targeted therapy for Gram-negative sepsis. Time-dependent killing properties of PTZ support the use of extended-infusion (EI) dosing; however, studies have shown inconsistent benefits of EI PTZ treatment on clinical outcomes.
Scott R, Cutro, Robert, Holzman, Yanina, Dubrovskaya, Xian Jie Cindy, Chen, Tania, Ahuja, Marco R, Scipione, Donald, Chen, John, Papadopoulos, Michael S, Phillips, Sapna A, Mehta   +9 more
openaire   +2 more sources

Optimizing Betalactam Clinical Response by Using a Continuous Infusion: A Comprehensive Review

Antibiotics, 2023
Introduction: Antimicrobial resistance is a major healthcare issue responsible for a large number of deaths. Many reviews identified that PKPD data are in favor of the use of continuous infusion, and we wanted to review clinical data results in order to ...
Sylvain Diamantis, Catherine Chakvetadze, Astrid de Pontfarcy, Matta Matta   +3 more
doaj   +1 more source

Extended Infusion of Dexmedetomidine to an Infant at Sixty Times the Intended Rate [PDF]

International Journal of Pediatrics, 2010
Dexmedetomidine is an 2 adrenergic agonist which has recently been approved in the United States for procedural sedation in adults. This report describes an infant who inadvertently received an intravenous infusion of dexmedetomidine at a rate which was 60 times greater than intended.
Bryan A. Max, Keira P. Mason
openaire   +3 more sources