Results 101 to 110 of about 209,873 (358)

Exosome-delivered microRNAs promote IFN-α secretion by human plasmacytoid DCs via TLR7 [PDF]

, 2018
The excessive production of type I IFNs is a hallmark and a main pathogenic mechanism of many autoimmune diseases, including systemic lupus erythematosus (SLE).
Andreoli, Laura, Bergese, Paolo, Bosisio, Daniela, Busatto, Sara, D'Oro, Ugo, Giannello, Veronica, Salvi, Valentina, Sozzani, Silvano, Tincani, Angela, Zingoni, Alessandra   +9 more
core   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

An extracellular vesicle delivery platform based on the PTTG1IP protein

Extracellular Vesicle
Extracellular vesicles (EVs) are promising therapeutic delivery vehicles, although their potential is limited by a lack of efficient engineering strategies to enhance loading and functional cargo delivery.
Carla Martin Perez, Xiuming Liang, Dhanu Gupta, Emily R. Haughton, Mariana Conceição, Imre Mäger, Samir EL Andaloussi, Matthew J.A. Wood, Thomas C. Roberts   +8 more
doaj  

Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer. [PDF]

, 2019
Many bacterial pathogens can cause septicemia and spread from the bloodstream into internal organs. During leptospirosis, individuals are infected by contact with Leptospira-containing animal urine-contaminated water.
Fang, Jia-Qi, Hu, Wei-Lin, Li, Kai-Xuan, Li, Shi-Jun, Li, Yang, Lin, Xu'ai, Ojcius, David M, Yan, Jie   +7 more
core   +1 more source

Extracellular matrix vesicles in human osteogenic neoplasms: An ultrastructural and enzymatic study [PDF]

, 1981
J. Sela, I. Bab, András Mühlrád, H Stein   +3 more
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Characterization of plasma-derived small extracellular vesicle miRNA and protein cargo in hereditary angioedema

Extracellular Vesicle
Hereditary angioedema (HAE) is an inherited disorder causing attacks of subcutaneous tissue or mucosa swelling. The disease burden and attack frequencies vary significantly among patients.
Linda Hofmann, Robin Lochbaum, Lutz Schütt, Ralph Röth, Stefanie Schmitteckert, Barbara Wollenberg, Thomas K. Hoffmann, Cornelia Brunner, Jens Greve, Janina Hahn, Marie-Nicole Theodoraki   +10 more
doaj  

Specific adherence of Borrelia burgdorferi extracellular vesicles to human endothelial cells in culture [PDF]

, 1993
R J Shoberg, D D Thomas
openalex   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

Extracellular vesicle lyophilization for enhanced distribution to the point of care

Extracellular Vesicle
Therapeutic extracellular vesicles (EVs) are in clinical trials and if successful, EVs wider use will be largely affected by costs to patients/insurers and accessibility.
Morgane E. Golan, Steven L. Stice
doaj