Results 111 to 120 of about 319,764 (352)

Preclinical translation of exosomes derived from mesenchymal stem/stromal cells. [PDF]

, 2020
Exosomes are nanovesicles secreted by virtually all cells. Exosomes mediate the horizontal transfer of various macromolecules previously believed to be cell-autonomous in nature, including nonsecretory proteins, various classes of RNA, metabolites, and ...
Anderson, Johnathon D, Elahi, Fanny M, Farwell, D Gregory, Nolta, Jan A   +3 more
core  

Biomimetic Iridescent Skin: Robust Prototissues Spontaneously Assembled from Photonic Protocells

Advanced Functional Materials, EarlyView.
Uniform nanoparticles are induced to form arrays (photonic crystals) in the cores of biopolymer capsules, endowing these ‘protocells’ with structural color. These protocells are then assembled into large self‐standing objects, i.e., prototissues, with robust mechanical properties as well as iridescent optical properties.
Medha Rath, Briahnah Streeter, Satyam Srivastava, Jemma Wood, William E. Bentley, Taylor J. Woehl, Srinivasa R. Raghavan   +6 more
wiley   +1 more source

Proteomic insights uncover enhanced neurotherapeutic potential in conditioned mesenchymal stem cell-derived extracellular vesicles

Extracellular Vesicle
Extracellular vesicles (EVs) show more potential as therapeutic agents for treating neurological disorders than their parent cells like MSCs. Notably, the therapeutic efficacy of MSCs can be boosted by inflammation factors and oxidative stressors.
Junxiu Xi, Tian Wang, Panpan Xian, Xiaoyan Liu, Minghao Du, Hao Yang, Perumal Palanisamy Chella, Wei Lin, Qianfa Long   +8 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Exploring emerging concepts of exosomes for the diagnosis, prognosis, and therapeutics of brain cancers

Extracellular Vesicle
Brain cancers, a global menace with high mortality rates, remain a profound challenge, particularly in treating the most lethal type of malignant tumors like glioblastoma multiforme (GBM).
Subhrajyoti Banerjee, Vriti Sharma, Chitrangada Das Mukhopadhyay   +2 more
doaj   +1 more source

Host- and Microbiota-Derived Extracellular Vesicles, Immune Function, and Disease Development [PDF]

, 2019
Laurence Macia, Ralph Nanan, Elham Hosseini‐Beheshti, Georges E. Grau   +3 more
openalex   +1 more source

Universal extracellular vesicles and PD-L1+ extracellular vesicles detected by single molecule array technology as circulating biomarkers for diffuse large B cell lymphoma [PDF]

, 2021
J Y Li, Di Shi, Xiaochun Wan, Jue Hu, Yifan Su, Yu-Peng Zeng, Zijuan Hu, Baohua Yu, Qunling Zhang, Ping Wei, Xiaoyan Zhou   +10 more
openalex   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Extracellular vesicles for breast cancer diagnosis and therapy

Extracellular Vesicle
Breast cancer is still suffering from its poor diagnosis and the lack of effective treatment. Despite of recent development of some novel chemicals, which are found to have inspiring therapeutic effects in vitro, their outcomes in clinic trails are ...
Jianan Shi, Huan Zhang, Yaxin Cui, Jianming Xing, Wei Wang, Jiayi Chen, Simiao Wang, Zhaogang Yang   +7 more
doaj   +1 more source

Size‐exclusion chromatography‐based enrichment of extracellular vesicles from urine samples [PDF]

, 2015
Inés Lozano‐Ramos, Ioana Bancu, Anna Oliveira‐Tercero, María Pilar Armengol, Armando Menezes‐Neto, Hernando A. del Portillo, Ricardo Lauzurica‐Valdemoros, Francesc E. Borràs   +7 more
openalex   +1 more source