Results 131 to 140 of about 209,873 (358)

An Active Form of Sphingosine Kinase-1 Is Released in the Extracellular Medium as Component of Membrane Vesicles Shed by Two Human Tumor Cell Lines [PDF]

open access: gold, 2010
Salvatrice Rigogliuso   +6 more
openalex   +1 more source

Cell Membrane Vesicle Camouflaged Artificial Cells

open access: yesAdvanced Functional Materials, EarlyView.
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres   +11 more
wiley   +1 more source

Mechanisms and potential of mesenchymal stem cell-derived exosomes for treating radiation-induced intestinal injury

open access: yesExtracellular Vesicle
Radiation-induced intestinal injury (RIII) is a prevalent complication of radiotherapy for abdominal and pelvic tumors, characterized by acute and chronic damage to intestinal tissues.
Tong An   +7 more
doaj  

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Extracellular vesicles on the wire [PDF]

open access: yesCell Adhesion & Migration, 2017
Vincent Hyenne, Jacky G. Goetz
openaire   +3 more sources

Immunogenicity of Extracellular Vesicles

open access: yesAdvanced Materials
AbstractExtracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery systems due to demonstrated safety and efficacy in preclinical models and early‐stage clinical trials. There is an urgent need to address the immunogenicity of EVs (beyond the apparent lack of immunotoxicity) to advance clinical development.
Yutian Xia   +3 more
openaire   +2 more sources

MicroRNAs won the Nobel Prize. Now, can extracellular vesicles help them become drugs?

open access: yesExtracellular Vesicle
The 2024 Nobel Prize recognized microRNAs (miRNAs) as transformative regulators of gene expression. However, their clinical potential has been constrained by instability and delivery challenges. Extracellular vesicles (EVs), as natural carriers of miRNAs,
Vanessa YiRan Li   +4 more
doaj  

Erratum to: Membrane Vesicles: A Common Feature in the Extracellular Matter of Cold-Adapted Antarctic Bacteria [PDF]

open access: bronze, 2010
Alina Frías   +4 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

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