Results 131 to 140 of about 236,767 (310)

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Brain Synapses: Neurons, Astrocytes, and Extracellular Vesicles in Health and Diseases [PDF]

Jacopo Meldolesi
openalex   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Isolation of extracellular vesicles from bitch’s amnion-derived cells culture and their CD59 expression: Preliminary results

, 2022
S Pastore, Alessandro Troisi, Rita Romani, Ilaria Bellezza, Marco Gargaro, Alessandra De Michele, Riccardo Orlandi, G. Guerrera, Marilena Bazzano, Angela Polisca   +9 more
openalex   +2 more sources

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

In Vitro Anticancer Activity of Extracellular Vesicles (EVs) Secreted by Gingival Mesenchymal Stromal Cells Primed with Paclitaxel [PDF]

, 2019
Valentina Coccè, Silvia Franzè, A.T. Brini, Aldo Bruno Giannì, Luisa Pascucci, Emilio Ciusani, Giulio Alessandri, Giampietro Farronato, Loredana Cavicchini, Valeria Sordi, Rita Paroni, Michele Dei, Francesco Cilurzo, Augusto Pessina   +13 more
openalex   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

Delivery of microRNAs by Extracellular Vesicles in Viral Infections: Could the News be Packaged? [PDF]

, 2019
Fábio Seiti Yamada Yoshikawa, Franciane Mouradian Emidio Teixeira, Maria Notomi Sato, Luanda Mara da Silva Oliveira   +3 more
openalex   +1 more source

Evaluation of Platelet-Derived Extracellular Vesicles in Gingival Fibroblasts and Keratinocytes for Periodontal Applications [PDF]

, 2022
Miquel Antich-Rosselló, Marta Munar‐Bestard, María Antonia Forteza‐Genestra, Javier Calvo, Antoni Gayà, Marta Monjo, Joana Maria Ramis   +6 more
openalex   +1 more source