Cell-to-Cell Communication in Learning and Memory: From Neuro- and Glio-Transmission to Information Exchange Mediated by Extracellular Vesicles [PDF]
Most aspects of nervous system development and function rely on the continuous crosstalk between neurons and the variegated universe of non-neuronal cells surrounding them.
Di Liegro, Carlo Maria+2 more
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Cornea organoids from human induced pluripotent stem cells. [PDF]
The cornea is the transparent outermost surface of the eye, consisting of a stratified epithelium, a collagenous stroma and an innermost single-cell layered endothelium and providing 2/3 of the refractive power of the eye. Multiple diseases of the cornea
Adams, Sheila M+5 more
core +7 more sources
Recent studies showed an unexpected complexity of extracellular vesicle (EV) biogenesis pathways. We previously found evidence that human colorectal cancer cells in vivo release large multivesicular body-like structures en bloc.
Tamás Visnovitz+14 more
doaj +1 more source
Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses. [PDF]
Extracellular RNAs (exRNAs) can be released by numerous cell types in vitro, are often protected within vesicles, and can modify recipient cell function. To determine how the composition and cellular sources of exRNAs and the extracellular vesicles (EVs)
Ansel, K Mark+6 more
core +1 more source
Extracellular vesicles and aging [PDF]
Aging and the chronic diseases associated with aging place a tremendous burden on our healthcare system. As our world population ages dramatically over the next decades, this will only increase. Hence, there is a great need to discover fundamental mechanisms of aging to enable development of strategies for minimizing the impact of aging on our health ...
openaire +3 more sources
Extracellular Vesicles in Renal Pathophysiology [PDF]
Extracellular vesicles are a heterogeneous population of microparticles released by virtually all living cells which have been recently widely investigated in different biological fields. They are typically composed of two primary types (exosomes and microvesicles) and are recently commanding increasing attention as mediators of cellular signaling ...
Pomatto, Margherita A. C.+3 more
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Extracellular vesicle-induced differentiation of neural stem progenitor cells [PDF]
Neural stem progenitor cells (NSPCs) from E13.5 mouse embryos can be maintained in culture under proliferating conditions. Upon growth-factor removal, they may differentiate toward either neuronal or glial phenotypes or both.
Biagioni, S.+5 more
core +1 more source
Immunotherapeutic Potential of Extracellular Vesicles [PDF]
Extracellular vesicle or EV is a term that encompasses all classes of secreted lipid membrane vesicles. Despite being scientific novelties, EVs are gaining importance as a mediator of important physiological and pathological intercellular activities possibly through the transfer of their cargo of protein and RNA between cells.
Ruenn Chai Lai+4 more
openaire +5 more sources
Reproducibility of extracellular vesicle research
Journal article: "Reproducibility of extracellular vesicle research"
Nieuwland, Rienk+3 more
openaire +5 more sources
Tumor-derived microvesicles modulate antigen cross-processing via reactive oxygen species-mediated alkalinization of phagosomal compartment in dendritic cells [PDF]
Dendritic cells (DCs) are the only antigen-presenting cells able to prime naïve T cells and cross-prime antigen-specific CD8+ T cells. Their functionality is a requirement for the induction and maintenance of long-lasting cancer immunity.
Aurelia Rughetti+16 more
core +2 more sources