Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels [PDF]
Important modulatory roles have been attributed to presynaptic NMDA receptors (NMDARs) located on cerebellar interneuron terminals. Evidence supporting a presynaptic location includes an increase in the frequency of mini events following the application ...
Benton, DCH+4 more
core +1 more source
Complex RNA world in small extracellular vesicles for liquid biopsy in cancer management
Liquid biopsy is a valuable tool in oncology with its advantages of non-invasiveness, longitudinal sampling, and capturing the intra- and inter-tumor heterogeneity. Small extracellular vesicles (sEVs) are released by cells into various biological fluids,
Shuhong Wang+6 more
doaj
Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization [PDF]
Initiation of mineralization during endochondral ossification is a multistep process and has been assumed to correlate with specific interactions of annexins A5 and A6 and collagens.
Anderson+54 more
core +1 more source
Sucrose-based cryoprotective storage of extracellular vesicles
Advancements in extracellular vesicle (EV) studies necessitate the development of optimized storage conditions to ensure preservation of physical and biochemical characteristics.
Sierra A. Walker+11 more
doaj
Exomap1 mouse: A transgenic model for in vivo studies of exosome biology
Exosomes are small extracellular vesicles (sEVs) of ∼30–150 nm in diameter that are enriched in exosome marker proteins and play important roles in health and disease.
Francis K. Fordjour+20 more
doaj
Extracellular matrix vesicles in human osteogenic neoplasms: An ultrastructural and enzymatic study [PDF]
J. Sela+3 more
openalex +1 more source
Engineered IL-15/IL-15Rα-expressing cellular vesicles promote T cell anti-tumor immunity
Interleukin 15 (IL-15) is a pivotal immune cytokine that responses to cancer stress signals and maintains tissue-resident memory T (TRM) cells. It is therefore considered as a potent therapeutic immunomodulator agonist cancer. However, in addition to the
Wenli Fang+10 more
doaj
Specific adherence of Borrelia burgdorferi extracellular vesicles to human endothelial cells in culture [PDF]
R J Shoberg, D D Thomas
openalex +1 more source
Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer. [PDF]
Many bacterial pathogens can cause septicemia and spread from the bloodstream into internal organs. During leptospirosis, individuals are infected by contact with Leptospira-containing animal urine-contaminated water.
Fang, Jia-Qi+7 more
core +1 more source
Evaluation and diagnostic potential of circulating extracellular vesicle-associated microRNAs in adrenocortical tumors [PDF]
There is no available blood marker for the preoperative diagnosis of adrenocortical malignancy. The objective of this study was to investigate the expression of extracellular vesicle-associated microRNAs and their diagnostic potential in plasma samples ...
A Strillacci+43 more
core +2 more sources