Results 101 to 110 of about 798,647 (298)

Exploring the Potential of Extracellular Vesicles from Atlantic Cod (Gadus morhua L.) Serum and Mucus for Wound Healing In Vitro

Biology
Novel therapeutic approaches for wound healing have included biomaterials from the Atlantic cod (Gadus morhua L.), with promising results in wound management.
Stefania D’Alessio, Igor Kraev, Bergljót Magnadóttir, Sigrun Lange   +3 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Metastatic colon cancer extracellular vesicles spread malignant properties in tumour microenvironment affecting the behaviour of both tumour and endothelial cells

, 2016
Metastatic colon cancer extracellular vesicles spread malignant properties in tumour microenvironment affecting the behaviour of both tumour and endothelial ...
Odessa Schillaci, Simona Taverna, Riccardo Alessandro, Simona Fontana, Francesca Monteleone, Dolores Di Vizio, Valentina Minciacchi   +6 more
core  

Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy

, 2021
Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer vaccine platform for efficiently provoking immune responses. However, OMV induce severe toxicity by activating the innate immune system.
Lötvall, Jan,, Svennerholm, Kristina,, Jan Lötvall, Crescitelli, Rossella,, Lässer, Cecilia,, Inta Gribonika, Rossella Crescitelli, Kristina Svennerholm, Kyong‐Su Park, Park, Kyong-Su,, Gribonika, Inta,, Cecilia Lässer   +11 more
core   +1 more source

Advances in Cellular Immune Theranostic Approaches for Glioblastoma: Current Trends and Future Directions

Cancer Innovation
Glioblastoma is a highly malignant type of brain tumor that remains one of the most challenging cancers to treat because of its aggressive nature, genetic heterogeneity, and immunosuppressive tumor microenvironment.
Ying Gong, Wanying Lin, Xuechun Fang, Ruyi Zhang, Min Luo, Haoran Wu, Shuai Chu, Chuangkun Li, Yiming Peng, Zhiyan Piao, Siping Wu, Junhao Li, ZongZhong He, Haixia Li, Hongxia Wang   +14 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The landscape of cellular immune alteration in systemic lupus erythematosus

Frontiers in Immunology
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multi-organ inflammation and profound immune dysregulation. Aberrant interactions among adaptive and innate immune cells—including T cells, B cells, dendritic cells ...
Jie Xiao, Jie Xiao, Lina Duan, Lina Duan, Jia Yang, Jia Yang, Yulu Deng, Yulu Deng, Shuyin Pang, Shuyin Pang, Hongxia Wang, Hongxia Wang, Xiaofeng Yin, Xiaofeng Yin, Haifang Wang, Haifang Wang, Yurong Qiu, Yurong Qiu, Xin Li, Xin Li, Ying Gong, Ying Gong, Ying Gong, Haixia Li, Haixia Li   +24 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Successful treatment of an NDM-5-producing, carbapenem-resistant Salmonella Kentucky ST198 infection with aztreonam and ceftazidime-avibactam in a patient with acute erythroid leukemia: a case report

BMC Infectious Diseases
Introduction Salmonella enterica serotype Kentucky (S. Kentucky) is a globally distributed food-borne zoonotic pathogen. It is increasingly associated with multi-drug resistance (MDR), notably to ciprofloxacin, a trend largely attributed to antibiotic ...
Yingcheng Qin, Li Lin, Hengrui Zhao, Xiumei Hu   +3 more
doaj   +1 more source