Results 111 to 120 of about 247,554 (291)

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Differential response of placental cells to high D‐glucose and its impact on extracellular vesicle biogenesis and trafficking via small GTPase Ras‐related protein RAB‐7A

Journal of Extracellular Biology
Placental extracellular vesicles (EVs) can be found in the maternal circulation throughout gestation, and their concentration, content and bioactivity are associated with pregnancy outcomes, including gestational diabetes mellitus (GDM).
Carlos Palma, Andrew Lai, Katherin Scholz‐Romero, Haarika Chittoory, Benjamin Van Haeringen, Flavio Carrion, Aase Handberg, Martha Lappas, Sunil R Lakhani, Amy E McCart Reed, H. David McIntyre, Soumyalekshmi Nair, Carlos Salomon   +12 more
doaj   +1 more source

Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats [PDF]

, 2018
Masatsugu Ohara, Shunsuke Ohnishi, Hidetaka Hosono, Koji Yamamoto, Kohei Yuyama, Hideki Nakamura, Qingjie Fu, Osamu Maehara, Goki Suda, Naoya Sakamoto   +9 more
openalex   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Serum extracellular vesicles contain SPARC and LRG1 as biomarkers of colon cancer and differ by tumour primary location [PDF]

, 2019
Min‐Er Zhong, Yanyu Chen, Yi Xiao, Lai Xu, Guannan Zhang, Junyang Lu, Huizhong Qiu, Wei Ge, Bin Wu   +8 more
openalex   +1 more source

Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia [PDF]

, 2022
Zhi Ruan, Kayo Takamatsu-Yukawa, Yuzhi Wang, Margaret Ushman, Adam Labadorf, Maria Ericsson, Seiko Ikezu, Tsuneya Ikezu   +7 more
openalex   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Effects of magnetic fields-stimulated 3D-Schwann cell-secreted extracellular vesicles regulate differentiation of neural stem cells and nerve regeneration

Materials & Design
The nerve guide conduit is a favorable implant for repairing peripheral nerve injuries, which is vital for promoting nerve regeneration. Therefore, we integrated magnetic 3D Schwann cells (SC) into a 3D-printed nerve conduit made from polyurethane to ...
Yueh-Sheng Chen, Jian-Jr Lee, Yen-Hong Lin, Yun-Jhen Lin, Min-Hua Yu, Cheng-Yu Chen, Der-Yang Cho, Ming-You Shie   +7 more
doaj   +1 more source

Cancer Cell Derived Small Extracellular Vesicles Contribute to Recipient Cell Metastasis Through Promoting HGF/c-Met Pathway* [PDF]

, 2019
Zhi Qiao, Yan Zhang, Maolin Ge, Sha Liu, Xiaoteng Jiang, Zhi Shang, Han Liu, Chengxi Cao, Hua Xiao   +8 more
openalex   +1 more source

High-Sensitivity Glycan Profiling of Blood-Derived Immunoglobulin G, Plasma, and Extracellular Vesicle Isolates with Capillary Zone Electrophoresis-Mass Spectrometry

, 2021
Anne‐Lise Marie, Somak Ray, Shulin Lu, Jennifer Jones, Ionita Ghiran, Alexander R. Ivanov   +5 more
openalex   +2 more sources