Results 21 to 30 of about 247,554 (291)

Extracellular Vesicles in Transplantation [PDF]

Frontiers in Immunology, 2022
Extracellular vesicles (EVs) have been extensively studied in the last two decades. It is now well documented that they can actively participate in the activation or regulation of immune system functions through different mechanisms, the most studied of which include protein–protein interactions and miRNA transfers.
Nicolas Sailliet, Matti Ullah, Amandine Dupuy, Amanda K. A. Silva, Florence Gazeau, Hoa Le Mai, Sophie Brouard, Sophie Brouard   +7 more
openaire   +5 more sources

Considerations for the Analysis of Small Extracellular Vesicles in Physical Exercise

Frontiers in Physiology, 2020
Physical exercise induces acute physiological changes leading to enhanced tissue cross-talk and a liberation of extracellular vesicles (EVs) into the circulation.
Alexandra Brahmer, Alexandra Brahmer, Elmo W. I. Neuberger, Perikles Simon, Eva-Maria Krämer-Albers   +4 more
doaj   +1 more source

Extracellular Vesicles Mediate Epimastigogenesis in Trypanosoma cruzi: Strain-Specific Dynamics and Temperature-Dependent Differentiation

Life
Trypanosoma cruzi, the causative agent of Chagas disease, undergoes epimastigogenesis—a critical differentiation step in which trypomastigotes transform into epimastigotes. While this process is essential for the parasite’s survival in its insect vector,
Abel Sana, Izadora Volpato Rossi, Bruna Sabatke, Marcel Ivan Ramirez   +3 more
doaj   +1 more source

Regulation and Roles of Metacyclogenesis and Epimastigogenesis in the Life Cycle of Trypanosoma cruzi

Pathogens
Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits remarkable developmental plasticity that enables its survival across distinct environments within the insect vector and mammalian host.
Abel Sana, Izadora Volpato Rossi, Marcel Ivan Ramirez   +2 more
doaj   +1 more source

Extracellular vesicle-embedded materials

Journal of Controlled Release, 2023
Extracellular vesicles (EVs) are small membrane-bound vesicles released by cells. EVs are emerging as a promising class of therapeutic entity that could be adapted in formulation due to their lack of immunogenicity and targeting capabilities. EVs have been shown to have similar regenerative and therapeutic effects to their parental cells and also have ...
Ma, Yingchang, Brocchini, Steve, Williams, Gareth R   +2 more
openaire   +3 more sources

NINJ1 oligomerises on large apoptotic cell-derived extracellular vesicles to regulate vesicle stability and cellular content release

Frontiers in Immunology
Billions of cells undergo apoptosis, a non-inflammatory form of programmed cell death, daily as part of normal development and homeostasis. Apoptotic cells undergo apoptotic cell disassembly to release large extracellular vesicles (EVs) called apoptotic ...
Bo Shi, Caolingzhi Tang, Stephanie F. Rutter, Omar Audi, Dilara C. Ozkocak, Alice M. Trenerry, Daniel S. Simpson, Scott A. Williams, Quan T. Le, Gemma F. Ryan, Ponsuge T. M. Cooray, James E. Vince, Jason M. Mackenzie, Mark D. Hulett, Thanh Kha Phan, Ivan K. H. Poon   +15 more
doaj   +1 more source

Extracellular Vesicles in Phylogeny

International Journal of Molecular Sciences, 2023
Extracellular vesicles (EVs) are cell-derived lipid vesicles in a size range of 20–1000 nm; often, these are classified as smaller and larger EVs in the literature or also commonly called small EVs (“exosomes”) and medium/large EVs (“microvesicles”) [...]
openaire   +2 more sources

Boosting extracellular vesicle secretion

Biotechnology Advances, 2022
In recent years, extracellular vesicles (EVs), specifically exosomes, have emerged as a promising strategy for treating a wide spectrum of pathologies, such as cancer and COVID-19, as well as promoting tissue regeneration in various conditions, including cardiomyopathies and spinal cord injuries.
Debbi, Lior, Guo, Shaowei, Safina, Dina, Levenberg, Shulamit   +3 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection

Scientific Reports
Traditional investigations of viral infection mechanisms have predominantly relied on two-dimensional (2D) cell culture models, which lack the structural organization and physiological relevance of native tissues.
Yi-Wen Chen, Huan-Jung Chiang, Kuan-Ting Liu, Chun-Wei Kao, Shan-Ren Xie, Chao-Ming Su, Yu-Yin Shih   +6 more
doaj   +1 more source