Results 21 to 30 of about 244,743 (291)

Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk

open access: yesScientific Reports, 2021
HIV and type 2 diabetes (T2D) are both associated with gut microbiota alterations, low-grade endotoxemia and increased cardiovascular risk. We investigated the potential role of plasma extracellular vesicles (EVs) in relation to these processes.
Beate Vestad   +12 more
doaj   +1 more source

Extracellular Vesicles as Regulators of the Extracellular Matrix

open access: yesBioengineering, 2023
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication. As EVs are released and move from parent to recipient cell, EVs interact with the extracellular matrix (ECM) which ...
Neil J. Patel   +2 more
openaire   +3 more sources

Extracellular Vesicles in Human Milk [PDF]

open access: yesPharmaceuticals, 2021
Milk supports the growth and development of infants. An increasing number of mostly recent studies have demonstrated that milk contains a hitherto undescribed component called extracellular vesicles (EVs). This presents questions regarding why milk contains EVs and what their function is. Recently, we showed that EVs in human milk expose tissue factor,
Yong Hu   +2 more
openaire   +4 more sources

Extracellular Vesicles in Angiogenesis

open access: yesCirculation Research, 2017
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies, microvesicles, and exosomes, have emerged as important players in cell-to-cell communication in normal physiology and pathological conditions. EVs encapsulate and convey various bioactive molecules that are further transmitted to neighboring or more distant cells ...
Todorova, Dilyana   +4 more
openaire   +2 more sources

Exploring differential gene expression and biomarker potential in systemic lupus erythematosus: a retrospective study [PDF]

open access: yesPeerJ
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by inflammation and immune-mediated multi-organ system damage, accompanied by clinical manifestations such as fever, hair loss, skin rash, oral ulcers, and joint ...
Jie Xiao   +9 more
doaj   +2 more sources

Extracellular vesicles and aging [PDF]

open access: yesStem Cell Investigation, 2017
Aging and the chronic diseases associated with aging place a tremendous burden on our healthcare system. As our world population ages dramatically over the next decades, this will only increase. Hence, there is a great need to discover fundamental mechanisms of aging to enable development of strategies for minimizing the impact of aging on our health ...
openaire   +2 more sources

Considerations for the Analysis of Small Extracellular Vesicles in Physical Exercise

open access: yesFrontiers in Physiology, 2020
Physical exercise induces acute physiological changes leading to enhanced tissue cross-talk and a liberation of extracellular vesicles (EVs) into the circulation.
Alexandra Brahmer   +4 more
doaj   +1 more source

Extracellular Vesicles Mediate Epimastigogenesis in Trypanosoma cruzi: Strain-Specific Dynamics and Temperature-Dependent Differentiation

open access: yesLife
Trypanosoma cruzi, the causative agent of Chagas disease, undergoes epimastigogenesis—a critical differentiation step in which trypomastigotes transform into epimastigotes. While this process is essential for the parasite’s survival in its insect vector,
Abel Sana   +3 more
doaj   +1 more source

Regulation and Roles of Metacyclogenesis and Epimastigogenesis in the Life Cycle of Trypanosoma cruzi

open access: yesPathogens
Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits remarkable developmental plasticity that enables its survival across distinct environments within the insect vector and mammalian host.
Abel Sana   +2 more
doaj   +1 more source

NINJ1 oligomerises on large apoptotic cell-derived extracellular vesicles to regulate vesicle stability and cellular content release

open access: yesFrontiers in Immunology
Billions of cells undergo apoptosis, a non-inflammatory form of programmed cell death, daily as part of normal development and homeostasis. Apoptotic cells undergo apoptotic cell disassembly to release large extracellular vesicles (EVs) called apoptotic ...
Bo Shi   +15 more
doaj   +1 more source

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