Results 61 to 70 of about 1,190,807 (310)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Nutritional properties of extracellular vesicle-like particles from Sophora flavescens and Periplaneta americana with effects on streptozotocin-induced diabetic wound healing in rats

Frontiers in Nutrition
IntroductionThe medicinal plant Sophora flavescens (SF) and the insect Periplaneta americana (PA) have long been used in treating diabetic wounds. PA-derived extracellular vesicle-like particles (PA-EVLP) can accelerate diabetic wound healing.
Zhengting Wu, Zhengting Wu, Zhengting Wu, Yuanxin Zhao, Yuanxin Zhao, Yuanxin Zhao, Weiyin Zeng, Weiyin Zeng, Weiyin Zeng, Zesheng Lu, Zesheng Lu, Zesheng Lu, Qi You, Qi You, Qi You, Yingqi Cao, Yingqi Cao, Yingqi Cao, Yuanyuan Xia, Yuanyuan Xia, Wencong Shen, Wencong Shen, Wencong Shen, Zilin Ou, Zilin Ou, Zilin Ou, Xiuping Cai, Xiuping Cai, Qing Zhao, Qing Zhao, Qing Zhao, Kewei Zhao, Kewei Zhao, Kewei Zhao   +33 more
doaj   +1 more source

Considerations for the Analysis of Small Extracellular Vesicles in Physical Exercise

Frontiers in Physiology, 2020
Physical exercise induces acute physiological changes leading to enhanced tissue cross-talk and a liberation of extracellular vesicles (EVs) into the circulation.
Alexandra Brahmer, Alexandra Brahmer, Elmo W. I. Neuberger, Perikles Simon, Eva-Maria Krämer-Albers   +4 more
doaj   +1 more source

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

Journal of Extracellular Vesicles, 2021
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of extracellular vesicles (EV) in urine opened a new fast‐growing scientific field.
U. Erdbrügger, C. Blijdorp, I. Bijnsdorp, F. Borràs, D. Burger, B. Bussolati, J. B. Byrd, A. Clayton, J. Dear, J. Falcón-Pérez, Cristina Grange, A. Hill, H. Holthöfer, E. Hoorn, G. Jenster, C. Jiménez, K. Junker, John Klein, M. Knepper, E. Koritzinsky, J. M. Luther, M. Lenassi, J. Leivo, I. Mertens, L. Musante, Eline Oeyen, M. Puhka, M. V. van Royen, Catherine Sánchez, Carolina Soekmadji, V. Thongboonkerd, V. van Steijn, G. Verhaegh, J. Webber, Kenneth W. Witwer, P. S. Yuen, Lei Zheng, A. Llorente, E. Martens-Uzunova   +38 more
semanticscholar   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Extracellular vesicles: the next generation in gene therapy delivery.

Molecular Therapy, 2023
Extracellular vesicles (EVs) are esteemed as a promising delivery vehicle for various genetic therapeutics. They are relatively inert, non-immunogenic, biodegradable, and biocompatible.
Riccardo Cecchin, Zach Troyer, Kenneth W. Witwer, Kevin V. Morris   +3 more
semanticscholar   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Understanding extracellular vesicles [PDF]

PROTEOMICS, 2021
David W. Greening, Richard J. Simpson
openaire   +2 more sources

Efferocytosis of apoptotic bodies drives SARS-CoV-2 infection and macrophage inflammation

Nature Communications
SARS-CoV-2 typically utilises host receptor angiotensin-converting enzyme 2 (ACE2) for viral entry. Despite low ACE2 expression, monocyte-derived macrophages, the predominant lung macrophage during severe COVID-19, are often found with SARS-CoV-2 in ...
Thanh Kha Phan, Dylan Sheerin, Bo Shi, Ngee K. Chua, Sriram Gummadi, Merle Dayton, Liana Mackiewicz, Ana Maluenda, Dilara C. Ozkocak, Georgia K. Atkin-Smith, Nashied Peton, Ching-Seng Ang, Omar Audi, Quan Thinh Le, Thu Uyen Tran, Tuong-Khanh My Tu, Rochelle Tixeira, George W. Ashdown, Kathryn C. Davidson, Pamali Fonseka, Rebecca Feltham, Marcel Doerflinger, Mark D. Hulett, Anna K. Coussens, Ivan K. H. Poon   +24 more
doaj   +1 more source