Toxoplasma gondii F-actin forms an extensive filamentous network required for material exchange and parasite maturation [PDF]
eLife, 2017 Apicomplexan actin is important during the parasite's life cycle. Its polymerization kinetics are unusual, permitting only short, unstable F-actin filaments.
Javier Periz +10 more
doaj +4 more sources
AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells [PDF]
Biology Open, 2012 Summary Remodeling of the actin cytoskeleton is required for vasopressin (VP)-induced aquaporin 2 (AQP2) trafficking. Here, we asked whether VP and forskolin (FK)-mediated F-actin depolymerization depends on AQP2 expression.
Naofumi Yui +3 more
doaj +4 more sources
Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]
, 2012 Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli +10 more
core +18 more sources
Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes. [PDF]
, 2020 The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-
Avilov, I. +6 more
core +1 more source
Actin structure-dependent stepping of myosin 5a and 10 during processive movement. [PDF]
PLoS ONE, 2013 How myosin 10, an unconventional myosin, walks processively along actin is still controversial. Here, we used single molecule fluorescence techniques, TIRF and FIONA, to study the motility and the stepping mechanism of dimerized myosin 10 heavy ...
Jianjun Bao +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Increasing evidence supports the notion that filamentous actin (F-actin) and globular actin exist in the nuclei of somatic cells, and are involved in chromatin remodeling, gene transcription regulation and DNA damage repair.
Wei Wu +13 more
doaj +1 more source
eLife, 2019 In addition to its role in erythrocyte invasion, Plasmodium falciparum actin is implicated in endocytosis, cytokinesis and inheritance of the chloroplast-like organelle called the apicoplast.
Johannes Felix Stortz +5 more
doaj +1 more source
Piccolo Directs Activity Dependent F-Actin Assembly from Presynaptic Active Zones via Daam1. [PDF]
PLoS ONE, 2015 The dynamic assembly of filamentous (F) actin plays essential roles in the assembly of presynaptic boutons, the fusion, mobilization and recycling of synaptic vesicles (SVs), and presynaptic forms of plasticity.
Dhananjay Wagh +6 more
doaj +1 more source
A Rho family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. [PDF]
, 2005 Tip growth in neuronal cells, plant cells, and fungal hyphae is known to require tip-localized Rho GTPase, calcium, and filamentous actin (F-actin), but how they interact with each other is unclear.
Dowd, Peter +6 more
core +3 more sources
Coordinated oscillations in cortical actin and Ca2+ correlate with cycles of vesicle secretion. [PDF]
, 2012 The actin cortex both facilitates and hinders the exocytosis of secretory granules. How cells consolidate these two opposing roles was not well understood. Here we show that antigen activation of mast cells induces oscillations in Ca(2+) and PtdIns(4,5)P(
Meyer, T, Wollman, R
core +1 more source