Results 21 to 30 of about 622,719 (265)

The Chlamydia trachomatis Early Effector Tarp Outcompetes Fascin in Forming F-Actin Bundles In Vivo

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
The intracellular pathogen Chlamydia trachomatis secretes multiple early effectors into the host cell to promote invasion. A key early effector during host cell entry, Tarp (translocated actin-recruiting phosphoprotein) is comprised of multiple protein ...
George F. Aranjuez   +2 more
doaj   +1 more source

Molecular mechanism for direct actin force-sensing by α-catenin

open access: yeseLife, 2020
The actin cytoskeleton mediates mechanical coupling between cells and their tissue microenvironments. The architecture and composition of actin networks are modulated by force; however, it is unclear how interactions between actin filaments (F-actin) and
Lin Mei   +5 more
doaj   +1 more source

F-actin in conifer roots [PDF]

open access: yesProceedings of the National Academy of Sciences, 1982
The distribution of F-actin in the complex tissues of a higher plant organ has been visualized by fluorescence labeling the roots of the conifers Chamaecyparis obtusa and Pseudotsuga menziesii with F-actin-specific fluorescent dye-conjugated phallicidin.
T C, Pesacreta   +3 more
openaire   +2 more sources

Nuclear Actin Polymerization Regulates Cell Epithelial‐Mesenchymal Transition

open access: yesAdvanced Science, 2023
Current studies on actin function primarily rely on cytoplasmic actin due to the absence of cellular models specifically expressing nuclear actin. Here, cell models capable of expressing varying levels of nuclear F/G‐actin are generated and a significant
William W. Du   +5 more
doaj   +1 more source

Mechanics of the F-actin cytoskeleton [PDF]

open access: yesJournal of Biomechanics, 2010
Dynamic regulation of the filamentous actin (F-actin) cytoskeleton is critical to numerous physical cellular processes, including cell adhesion, migration and division. Each of these processes require precise regulation of cell shape and mechanical force generation which, to a large degree, is regulated by the dynamic mechanical behaviors of a diverse ...
Jonathan, Stricker   +2 more
openaire   +2 more sources

Hsp27-Actin Interaction

open access: yesBiochemistry Research International, 2011
Hsp27 oligomer is reported to interact with F-actin as a barbed-end-capping protein. The present study determined the binding strength and stoichiometry of the interaction using fluorescence of probes attached to Hsp27 cysteine-137.
Philip Graceffa
doaj   +1 more source

Adhesive F-actin waves: a novel integrin-mediated adhesion complex coupled to ventral actin polymerization. [PDF]

open access: yesPLoS ONE, 2011
At the leading lamellipodium of migrating cells, protrusion of an Arp2/3-nucleated actin network is coupled to formation of integrin-based adhesions, suggesting that Arp2/3-mediated actin polymerization and integrin-dependent adhesion may be ...
Lindsay B Case, Clare M Waterman
doaj   +1 more source

Actin polymerization and depolymerization in developing vertebrates

open access: yesFrontiers in Physiology, 2023
Development is a complex process that occurs throughout the life cycle. F-actin, a major component of the cytoskeleton, is essential for the morphogenesis of tissues and organs during development.
Yang Bai   +14 more
doaj   +1 more source

Tracer Studies on F-Actin Fluctuations [PDF]

open access: yesPhysical Review Letters, 2002
We present a study on the fluctuations of semiflexible actin filaments using fluorescence videomicroscopy, focusing on the end-to-end fluctuations of single filaments. In order to specifically measure the position of the polymer's ends, we developed a novel noninvasive method that consists of annealing short end tags to the filaments. This allows us to
Le Goff, Loïc   +3 more
openaire   +5 more sources

F-Actin Dynamics in Neurospora crassa [PDF]

open access: yesEukaryotic Cell, 2010
ABSTRACT This study demonstrates the utility of Lifeact for the investigation of actin dynamics in Neurospora crassa and also represents the first report of simultaneous live-cell imaging of the actin and microtubule cytoskeletons in filamentous fungi.
Berepiki, Adokiye   +4 more
openaire   +4 more sources

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