Results 21 to 30 of about 622,719 (265)
The Chlamydia trachomatis Early Effector Tarp Outcompetes Fascin in Forming F-Actin Bundles In Vivo
The intracellular pathogen Chlamydia trachomatis secretes multiple early effectors into the host cell to promote invasion. A key early effector during host cell entry, Tarp (translocated actin-recruiting phosphoprotein) is comprised of multiple protein ...
George F. Aranjuez +2 more
doaj +1 more source
Molecular mechanism for direct actin force-sensing by α-catenin
The actin cytoskeleton mediates mechanical coupling between cells and their tissue microenvironments. The architecture and composition of actin networks are modulated by force; however, it is unclear how interactions between actin filaments (F-actin) and
Lin Mei +5 more
doaj +1 more source
F-actin in conifer roots [PDF]
The distribution of F-actin in the complex tissues of a higher plant organ has been visualized by fluorescence labeling the roots of the conifers Chamaecyparis obtusa and Pseudotsuga menziesii with F-actin-specific fluorescent dye-conjugated phallicidin.
T C, Pesacreta +3 more
openaire +2 more sources
Nuclear Actin Polymerization Regulates Cell Epithelial‐Mesenchymal Transition
Current studies on actin function primarily rely on cytoplasmic actin due to the absence of cellular models specifically expressing nuclear actin. Here, cell models capable of expressing varying levels of nuclear F/G‐actin are generated and a significant
William W. Du +5 more
doaj +1 more source
Mechanics of the F-actin cytoskeleton [PDF]
Dynamic regulation of the filamentous actin (F-actin) cytoskeleton is critical to numerous physical cellular processes, including cell adhesion, migration and division. Each of these processes require precise regulation of cell shape and mechanical force generation which, to a large degree, is regulated by the dynamic mechanical behaviors of a diverse ...
Jonathan, Stricker +2 more
openaire +2 more sources
Hsp27 oligomer is reported to interact with F-actin as a barbed-end-capping protein. The present study determined the binding strength and stoichiometry of the interaction using fluorescence of probes attached to Hsp27 cysteine-137.
Philip Graceffa
doaj +1 more source
Adhesive F-actin waves: a novel integrin-mediated adhesion complex coupled to ventral actin polymerization. [PDF]
At the leading lamellipodium of migrating cells, protrusion of an Arp2/3-nucleated actin network is coupled to formation of integrin-based adhesions, suggesting that Arp2/3-mediated actin polymerization and integrin-dependent adhesion may be ...
Lindsay B Case, Clare M Waterman
doaj +1 more source
Actin polymerization and depolymerization in developing vertebrates
Development is a complex process that occurs throughout the life cycle. F-actin, a major component of the cytoskeleton, is essential for the morphogenesis of tissues and organs during development.
Yang Bai +14 more
doaj +1 more source
Tracer Studies on F-Actin Fluctuations [PDF]
We present a study on the fluctuations of semiflexible actin filaments using fluorescence videomicroscopy, focusing on the end-to-end fluctuations of single filaments. In order to specifically measure the position of the polymer's ends, we developed a novel noninvasive method that consists of annealing short end tags to the filaments. This allows us to
Le Goff, Loïc +3 more
openaire +5 more sources
F-Actin Dynamics in Neurospora crassa [PDF]
ABSTRACT This study demonstrates the utility of Lifeact for the investigation of actin dynamics in Neurospora crassa and also represents the first report of simultaneous live-cell imaging of the actin and microtubule cytoskeletons in filamentous fungi.
Berepiki, Adokiye +4 more
openaire +4 more sources

