Results 21 to 30 of about 662,881 (280)
Multiple Roles of Actin in Exo- and Endocytosis
Frontiers in Synaptic Neuroscience, 2022 Cytoskeletal filamentous actin (F-actin) has long been considered a molecule that may regulate exo- and endocytosis. However, its exact roles remained elusive.
Ling-Gang Wu, Chung Yu Chan
doaj +1 more source
Tube Width Fluctuations in F-Actin Solutions [PDF]
, 2010 We determine the statistics of the local tube width in F-actin solutions, beyond the usually reported mean value. Our experimental observations are explained by a segment fluid theory based on the binary collision approximation (BCA).
B. Hoffmann +9 more
core +2 more sources
eLife, 2019 We previously discovered that competition between fission yeast actin binding proteins (ABPs) for binding F-actin facilitates their sorting to different cellular networks.
Jenna R Christensen +7 more
doaj +1 more source
Sensing Actin Dynamics through Adherens Junctions
Cell Reports, 2020 Summary: We study punctate adherens junctions (pAJs) to determine how short-lived cadherin clusters and relatively stable actin bundles interact despite differences in dynamics.
Indrajyoti Indra +4 more
doaj +1 more source
PLoS Genetics, 2022 Actin cytoskeleton is essential for root hair formation. However, the underlying molecular mechanisms of actin dynamics in root hair formation in response to abiotic stress are largely undiscovered. Here, genetic analysis showed that actin-depolymerizing
Shuangtian Bi +11 more
doaj +1 more source
Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility. [PDF]
, 2011 BackgroundCell migration plays an important role in many physiological and pathological processes, including immune cell chemotaxis and cancer metastasis.
Liao, Kan, Liu, Yang, Wang, Wenqi
core +2 more sources
eLife, 2017 The fission yeast actin cytoskeleton is an ideal, simplified system to investigate fundamental mechanisms behind cellular self-organization. By focusing on the stabilizing protein tropomyosin Cdc8, bundling protein fimbrin Fim1, and severing protein ...
Jenna R Christensen +6 more
doaj +1 more source
The Chlamydia trachomatis Early Effector Tarp Outcompetes Fascin in Forming F-Actin Bundles In Vivo
Frontiers in Cellular and Infection Microbiology, 2022 The intracellular pathogen Chlamydia trachomatis secretes multiple early effectors into the host cell to promote invasion. A key early effector during host cell entry, Tarp (translocated actin-recruiting phosphoprotein) is comprised of multiple protein ...
George F. Aranjuez +2 more
doaj +1 more source
Multiple Conformations of F-actin [PDF]
Structure, 2010 Actin works within eukaryotic cells to facilitate a variety of cellular processes, which are driven by the assembly of G-actin (monomeric form) into F-actin (fibrous form), and the disassembly of F-actin into G-actin. F-actin adopts multiple conformations, which are specified by interactions with various actin-binding proteins.
Oda, Toshiro, Maéda, Yuichiro
openaire +2 more sources
Molecular mechanism for direct actin force-sensing by α-catenin
eLife, 2020 The actin cytoskeleton mediates mechanical coupling between cells and their tissue microenvironments. The architecture and composition of actin networks are modulated by force; however, it is unclear how interactions between actin filaments (F-actin) and
Lin Mei +5 more
doaj +1 more source