Results 111 to 120 of about 13,969 (210)
Epigenetic regulation of fatty acid amide hydrolase in Alzheimer disease.
PLoS ONE, 2012 ObjectiveAlzheimer disease (AD) is a progressive, degenerative and irreversible neurological disorder with few therapies available. In search for new potential targets, increasing evidence suggests a role for the endocannabinoid system (ECS) in the ...
Claudio D'Addario +10 more
doaj +1 more source
Design, synthesis and biological evaluation of heterocyclic derivatives as potential MAGL inhibitors. [PDF]
, 2012 Facoltà di Farmacia Corso di laurea in Chimica e tecnologia farmaceutica; Relatore: prof.ssa C.Manera, dott.ssa F.Castelli; SSD: CHIM 08 Candidato: Gianfilippo Martello Titolo tesi: Design, synthesis and biological evaluation of heterocyclic derivatives ...
MARTELLO, GIANFILIPPO
core
Design and Synthesis of New A2B Adenosine Receptor Antagonists [PDF]
, 2009 Starting from chemical structure of N-benzo-[1,3]dioxol-5-yl-2-[5-(2,6dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol3-yloxy]-acetamide, MRE2029F20* various structural modifications were realized to afford a new series of A2B ...
BARALDI, Stefania
core
Cannabinoidok szerepe a traumák által előidézett viselkedési zavarok kialakulásában = The role of cannabinoids in the development of trauma-induced behavioral deficits [PDF]
, 2012 A projekt fontos felismerése, hogy a traumák által előidézett poszt-traumás stressz zavar-szerű viselkedési zavarok neuronális háttere erősen függ a traumatikus élmény jellegétől, és attól a kihívástól, amelyet a kísérleti szituáció jelent. Sőt, a trauma
Barna, István +5 more
core
FAAH Inhibition Counteracts Neuroinflammation via Autophagy Recovery in AD Models
International Journal of Molecular SciencesEndocannabinoids have attracted great interest for their ability to counteract the neuroinflammation underlying Alzheimer’s disease (AD). Our study aimed at evaluating whether this activity was also due to a rebalance of autophagic mechanisms in cellular and animal models of AD. We supplied URB597, an inhibitor of Fatty-Acid Amide Hydrolase (FAAH), the
Federica Armeli +7 more
openaire +5 more sources
FAAH-like anandamide transporter (FLAT) [PDF]
Science-Business eXchange, 2011 openaire +1 more source
The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways [PDF]
, 2009 Heather B Bradshaw +8 more
core +1 more source
Az endocannabinoid rendszer vizsgálata praeeclampsiában [PDF]
, 2016 Fügedi, Gergely
core +1 more source