Results 91 to 100 of about 9,726 (170)

IL-4 affects FAAH activity in prostate cancer cells.

open access: yes, 2013
Panel A, IL-4 receptor immunoreactivity in a prostate tumour tissue sample (Gleason score 8). The line at the bottom left of the picture represents 100 µm.
Lina Thors (362367)   +7 more
core   +1 more source

Lipid metabolism-derived FAAH is a sensitive marker for the prognosis and immunotherapy of osteosarcoma patients

open access: yesHeliyon
Lipid metabolism in cancer refers to the alterations in how cancer cells process and utilize lipids, a type of fat molecule. It was investigated how lipid metabolism relates to osteosarcoma.
Yanbin Shi   +4 more
doaj   +1 more source

FAAH immunoreactivity in formalin-foxed prostate cancer samples.

open access: yes, 2013
Panel A. Example of FAAH-IR in a core of non-malignant prostate tissue obtained at transurethral resection from a 75 year old patient. The asterisks indicate blood vessels, and the # symbol indicates FAAH positive cells, presumably infiltrating ...
Lina Thors (362367)   +7 more
core   +1 more source

Inhibiting Fatty Acid Amide Hydrolase (FAAH) Induces Apoptosis in Breast Cancer Cells [PDF]

open access: yes, 2020
Background: Breast cancer is a highly heterogeneous, aggressive disease that has poor prognosis. Current treatment is present, but research on a therapeutic alternative is ongoing.
Tripathy, Mallika   +1 more
core  

Epigenetic regulation of fatty acid amide hydrolase in Alzheimer disease.

open access: yesPLoS ONE, 2012
ObjectiveAlzheimer disease (AD) is a progressive, degenerative and irreversible neurological disorder with few therapies available. In search for new potential targets, increasing evidence suggests a role for the endocannabinoid system (ECS) in the ...
Claudio D'Addario   +10 more
doaj   +1 more source

Switching cannabinoid response from CB2 agonists to FAAH inhibitors

open access: yes, 2014
International audienceA series of 3-carboxamido-5-aryl-isoxazoles designed as CB2 agonists were evaluated as FAAH inhibitors. The pharmacological results led to identify structure-activity relationships enabling to switch cannabinoid response from CB2 ...
Andrzejak, Virginie   +9 more
core   +1 more source

Genetic and epigenetic regulation of faah gene.

open access: yes, 2013
a: Levels of FAAH mRNA in PBMCs from LOAD patients (n = 13) and controls (n = 12); b: Amount of methylated DNA at faah gene in controls (n = 33 ) and LOAD subjects (n = 33); c: Correlation between faah gene expression and % change of DNA methylation in ...
Daniela Galimberti (253047)   +10 more
core   +1 more source

PERIPHERALLY RESTRICTED FAAH INHIBITORS

open access: yes, 2012
Peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH) are provided. The compounds can suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS).
Guillermo MORENO SANZ   +6 more
core  

Enzyme Kinetics of FAAH

open access: yes
Anandamide (AEA) is an endogenous ethanolamide that functions as a signaling molecule within the endocannabinoid system, a regulatory network processes including pain perception, mood regulation, appetite, and neural signaling.
Stell, Susanna, Hooks, Emma
core  

Fenyylikarbamaattien kiraaliset oksatsoliinijohdannaiset potentiaalisina FAAH-inhibiittoreina: suunnittelu, synteesi ja karakterisointi

open access: yes, 2007
Diplomityön tarkoituksena oli suunnitella ja valmistaa molekyylikirjasto, jonka yhdisteet olisivat potentiaalisia inhibiittoreita endogeenista kannabinoidia arakidonoyylietanoliamidia hydrolysoivalle FAAH-entsyymille.
Kataja, Antti
core   +1 more source

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