Results 91 to 100 of about 9,726 (170)
IL-4 affects FAAH activity in prostate cancer cells.
Panel A, IL-4 receptor immunoreactivity in a prostate tumour tissue sample (Gleason score 8). The line at the bottom left of the picture represents 100 µm.
Lina Thors (362367) +7 more
core +1 more source
Lipid metabolism in cancer refers to the alterations in how cancer cells process and utilize lipids, a type of fat molecule. It was investigated how lipid metabolism relates to osteosarcoma.
Yanbin Shi +4 more
doaj +1 more source
FAAH immunoreactivity in formalin-foxed prostate cancer samples.
Panel A. Example of FAAH-IR in a core of non-malignant prostate tissue obtained at transurethral resection from a 75 year old patient. The asterisks indicate blood vessels, and the # symbol indicates FAAH positive cells, presumably infiltrating ...
Lina Thors (362367) +7 more
core +1 more source
Inhibiting Fatty Acid Amide Hydrolase (FAAH) Induces Apoptosis in Breast Cancer Cells [PDF]
Background: Breast cancer is a highly heterogeneous, aggressive disease that has poor prognosis. Current treatment is present, but research on a therapeutic alternative is ongoing.
Tripathy, Mallika +1 more
core
Epigenetic regulation of fatty acid amide hydrolase in Alzheimer disease.
ObjectiveAlzheimer disease (AD) is a progressive, degenerative and irreversible neurological disorder with few therapies available. In search for new potential targets, increasing evidence suggests a role for the endocannabinoid system (ECS) in the ...
Claudio D'Addario +10 more
doaj +1 more source
Switching cannabinoid response from CB2 agonists to FAAH inhibitors
International audienceA series of 3-carboxamido-5-aryl-isoxazoles designed as CB2 agonists were evaluated as FAAH inhibitors. The pharmacological results led to identify structure-activity relationships enabling to switch cannabinoid response from CB2 ...
Andrzejak, Virginie +9 more
core +1 more source
Genetic and epigenetic regulation of faah gene.
a: Levels of FAAH mRNA in PBMCs from LOAD patients (n = 13) and controls (n = 12); b: Amount of methylated DNA at faah gene in controls (n = 33 ) and LOAD subjects (n = 33); c: Correlation between faah gene expression and % change of DNA methylation in ...
Daniela Galimberti (253047) +10 more
core +1 more source
PERIPHERALLY RESTRICTED FAAH INHIBITORS
Peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH) are provided. The compounds can suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS).
Guillermo MORENO SANZ +6 more
core
Anandamide (AEA) is an endogenous ethanolamide that functions as a signaling molecule within the endocannabinoid system, a regulatory network processes including pain perception, mood regulation, appetite, and neural signaling.
Stell, Susanna, Hooks, Emma
core
Diplomityön tarkoituksena oli suunnitella ja valmistaa molekyylikirjasto, jonka yhdisteet olisivat potentiaalisia inhibiittoreita endogeenista kannabinoidia arakidonoyylietanoliamidia hydrolysoivalle FAAH-entsyymille.
Kataja, Antti
core +1 more source

