Results 81 to 90 of about 8,951 (213)

Effects of pharmacological inhibition of fatty acid amide hydrolase on corticosterone release: a systematic review of preclinical studies

Discover Mental Health
Psychiatric conditions are often linked to dysfunction of the Hypothalamic–Pituitary–Adrenal (HPA) axis. The Endocannabinoid System (ECS) plays a significant role in stress and anxiety and interacts with the HPA axis.
Christina F. Pereira, Isabelle Boileau, Stefan Kloiber   +2 more
doaj   +1 more source

Expression of FAAH and FLAT in cell-lines.

, 2013
(A) Western blot of FAAH and FLAT expression in brain, HeLa cells transfected with FAAH (0.15 µg) or FLAT (1.5 µg), and in N18TG2 neuroblastoma and CCF-STTG1 astrocytoma cells. (B) Expression of FAAH and FLAT following transfection into HEK-293 cells. (C)
Sherrye T. Glaser (479290), Matthew W. Elmes (479289), Dale G. Deutsch (295241), Martin Kaczocha (295232), KwanNok Leung (479288)   +4 more
core   +1 more source

Immunohistochemical staining for FAAH.

, 2013
Images on the left side of the panel represent the negative control (non-immune rabbit serum and images on the right are for FAAH. Images a and b are primordial follicle; c and d are primary follicles; e and f are secondary follicles; g and h are low ...
Mona R. El-Talatini (374359), Justin C. Konje (374363), Janine C. Elson (374361), Laurence Brown (43103), Allan C. Davidson (374362), Anthony H. Taylor (374360)   +5 more
core   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Combined FAAH and COX inhibition by Flurbiprofen amide derivatives for the treatment of pain and inflammation

, 2019
Nonsteroidal anti‐inflammatory drugs (NSAIDs) – such as ibuprofen and flurbiprofen – are non-selective COX inhibitors widely used to treat acute and chronic pain.
Fowler CJ, Deplano A, Catalanotti B, Moraca F, Morgillo CM, Novellino E, Onnis V   +6 more
core  

Association of FAAH-IR with prostate cancer outcome.

, 2013
Panel A. Receiver-operated characteristic (ROC) analyses for tumour epithelial (Epi) and blood vessel (BV) FAAH-IR. A 15 year cut-off was used for the patients who were not treated.
Lina Thors (362367), Christopher J. Fowler (124329), Peter Hammarsten (124310), Lars Egevad (124325), Emma Persson (362368), Torvald Granfors (124326), Pär Stattin (124323), Anders Bergh (175717)   +7 more
core   +1 more source

The anti-inflammatory and analgesic potential of the probiotic Streptococcus thermophilus via inhibition of endocannabinoid-degrading enzymes: a preliminary in vitro study [PDF]

Exploration of Immunology
Aim: The benefit of topical application of probiotics on pain and itching associated with skin disorders has become an increasingly intriguing topic in recent years.
Serena Altamura, Elona Dybeli, Francesca Lombardi, Paola Palumbo, Francesca Rosaria Augello, Skender Topi, Maria Grazia Cifone, Benedetta Cinque   +7 more
doaj   +1 more source

Towards Mechanism‐Informed Treatments for Mental Health

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuropsychiatric disorders impose a major global health burden, and current treatments, which historically mostly targeted dopamine and serotonin dysfunctions, often provide only partial, symptomatic relief. This review highlights emerging evidence that additional neuromodulator systems, including acetylcholine, norepinephrine, and endocannabinoids ...
Iker Bengoetxea de Tena, Farhanah Nabilah Sallie, Arvie Rodriguez Abiero, Beatrice Rizzi, Leandro Gabriel Champarini, Elisa Corti, Gianluca Masella, Ariel L. Dunn, Luisa Bandeira Binder, Tyler J. Wenzel, Agustin I. Robles, Roberta G. Anversa, Cécilia Tremblay, Aliance Romain Fokoua, Randriely Merscher Sobreira de Lima, Mateus D'Ávila, Trang T. T. Truong, Jessica C. Pierce, Rui S. Rodrigues, Luis Dinamarca‐Villarroel, Felipe Borges Almeida, Aino‐Kaisa Piironen, Andrey F. L. Aguiar, Andrés M. Jaramillo, Lucas Santos, Anja de Lange, David J. Nutt, Andrew J. Lawrence   +27 more
wiley   +1 more source

Fatty acid ethanolamides and FAAH inhibitor URB597.

, 2015
Fatty acid ethanolamides and FAAH inhibitor URB597.
Lisa Flammini (226054), Federica Vacondio (751463), Caterina Carmi (751467), Claudia Silva (751465), Riccardo Castelli (751466), Michele Bassi (751464), Laura Scalvini (751468), Silvia Rivara (751470), Alessio Lodola (180741), Valentina Vivo (751469), Marco Mor (180752), Elisabetta Barocelli (226056)   +11 more
core   +1 more source

Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity

BMC Medical Genetics, 2010
Background The orexigenic effects of cannabinoids are limited by activation of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH).
Rief Winfried, Scherag Susann, Vogel Carla IG, Grallert Harald, Scherag André, Greene Brandon H, Nguyen Trang T, Carrie Jophia, Wandolski Melanie, Brönner Günter, Müller Timo D, Wichmann Hans-Erich, Illig Thomas, Schäfer Helmut, Hebebrand Johannes, Hinney Anke   +15 more
doaj   +1 more source