Results 221 to 230 of about 28,235,749 (276)

ATF3 Promotes Solasonine-Triggered Ferroptosis in Glioma Cells by Suppressing Glycolysis. [PDF]

open access: yesCNS Neurosci Ther
Jia M   +8 more
europepmc   +1 more source

Report on factor H-related proteins as promoters of complement attack (D2.10)

open access: yes
Report on whether factor H-related proteins are potent boosters for promoting complement attack against microbes (by ESR FI2)
openaire   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

TRIM65-BTG3-HIF-1α axis drives osteosarcoma progression <i>via</i> M2 macrophage polarization and angiogenesis. [PDF]

open access: yesJ Transl Int Med
Wang H   +11 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Possible Relevance of Hepatoma-derived Growth Factor and Alkylglycerone Phosphate Synthase to Pancreatic Cancer Progression. [PDF]

open access: yesIn Vivo
Enomoto H   +10 more
europepmc   +1 more source

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