ATF3 Promotes Solasonine-Triggered Ferroptosis in Glioma Cells by Suppressing Glycolysis. [PDF]
Jia M +8 more
europepmc +1 more source
Report on factor H-related proteins as promoters of complement attack (D2.10)
Report on whether factor H-related proteins are potent boosters for promoting complement attack against microbes (by ESR FI2)
openaire +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Cloning, Expression Analysis, and Functional Characterization of the NAC Transcription Factor <i>SlNAC2-like</i> from Tomato. [PDF]
Lv L +5 more
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Effects of increasing concentrations of α-tocopherol on proliferating primary ovine satellite cells and abundance of transcripts associated with myogenic progression. [PDF]
Blad TJ +6 more
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
TRIM65-BTG3-HIF-1α axis drives osteosarcoma progression <i>via</i> M2 macrophage polarization and angiogenesis. [PDF]
Wang H +11 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Possible Relevance of Hepatoma-derived Growth Factor and Alkylglycerone Phosphate Synthase to Pancreatic Cancer Progression. [PDF]
Enomoto H +10 more
europepmc +1 more source

