Results 91 to 100 of about 356 (134)

The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases? [PDF]

J Clin Med, 2021
Poppelaars F, Faria B, Schwaeble W, Daha MR.   +3 more
europepmc   +1 more source

Current Understanding of Complement Proteins as Therapeutic Targets for the Treatment of Immunoglobulin A Nephropathy. [PDF]

Drugs, 2023
Rajasekaran A, Green TJ, Renfrow MB, Julian BA, Novak J, Rizk DV.   +5 more
europepmc   +1 more source

Factor H-related 1 and heparan sulfate architecture contribute to complement dysregulation in C3 glomerulopathy. [PDF]

Front Immunol
Slagle AK, Ghiringhelli Borsa N, Wang K, Taylor AO, Meyer NC, Jones MB, Walls WD, Nelson AFM, Roberts SM, Sun M, Goicoechea de Jorge E, Rodriguez de Cordoba S, Jalal DI, Nester CM, Zhang Y, Smith RJH.   +15 more
europepmc   +1 more source

Targeting complement in IgA nephropathy. [PDF]

Clin Kidney J, 2023
Caravaca-Fontán F, Gutiérrez E, Sevillano ÁM, Praga M.   +3 more
europepmc   +1 more source

Levels of soluble complement regulators predict severity of COVID-19 symptoms. [PDF]

Front Immunol, 2022
Tierney AL, Alali WM, Scott T, Rees-Unwin KS, CITIID-NIHR BioResource COVID-19 Collaboration, Clark SJ, Unwin RD.   +6 more
europepmc   +1 more source

Friend or foe: assessing the value of animal models for facilitating clinical breakthroughs in complement research. [PDF]

J Clin Invest
Poppelaars F, Holers VM, Thurman JM.
europepmc   +1 more source

The human complement factor H-related protein FHR-2 enhances complement activation on host and bacterial ligands

Immunobiology
Andrea E. Schneider, Marcell Cserhalmi, Domonkos Czárán, Csenge Réka Papp, Dániel Bencze, Dávid Szakács, Barbara Uzonyi, Mihály Józsi   +7 more
openaire   +1 more source

Mechanisms by which Factor H protects Trypanosoma cruzi from the alternative pathway of complement. [PDF]

Front Immunol
Menon SS, Ramirez-Toloza G, Wycoff KL, Ehinger S, Shaughnessy J, Ram S, Ferreira VP.   +6 more
europepmc   +1 more source

Factor H-related 2 levels dictate FHR dimer composition. [PDF]

Sci Rep
Veuskens BRJ, Brouwer MC, van Mierlo G, Geissler J, van Leeuwen K, Derlagen M, Keijzer NCH, Hoogenboezem M, Kuijpers TW, Pouw RB.   +9 more
europepmc   +1 more source

CTx001 for Geographic Atrophy: A Gene Therapy Expressing Soluble, Truncated Complement Receptor 1 (Mini-CR1). [PDF]

Ophthalmol Sci
Rathi S, Didangelos A, Pisarenka S, Green R, Zafeiri S, Emery-Billcliff P, Patel N, Whalley P, Zamiri P, Tilakaratna V, Szula E, Hasan R, Munye MM, Unwin RD, Bishop PN, Keefe D, Clark SJ.   +16 more
europepmc   +1 more source