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Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis. [PDF]
Matola AT +6 more
europepmc +1 more source
Inborn errors of immunity with kidney and urinary tract disorders: a review. [PDF]
Shajari A +8 more
europepmc +1 more source
Factor H-related proteins determine complement-activating surfaces [PDF]
Complement factor H-related proteins (FHRs) are strongly associated with different diseases involving complement dysregulation, which suggests a major role for these proteins regulating complement activation.
Mihály Jozsi +2 more
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Biochemical and functional characterization of the factor-H-related protein 4 (FHR-4)
Immunopharmacology, 1997Factor-H-related proteins and the complement regulatory protein factor H represent a family of structurally and immunologically related plasma proteins. The function of the various factor-H-related proteins are currently unclear and under investigation.
J, Hellwage, C, Skerka, P F, Zipfel
openaire +2 more sources
2023
Abstract Introduction Factor H-related proteins (FHRs) have emerged as novel players in complement-mediated diseases, as they exhibit structural resemblances to factor H but lack the regulatory domains, enabling them to antagonize factor H and increase complement activation through several activities.
Felix Poppelaars +10 more
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Abstract Introduction Factor H-related proteins (FHRs) have emerged as novel players in complement-mediated diseases, as they exhibit structural resemblances to factor H but lack the regulatory domains, enabling them to antagonize factor H and increase complement activation through several activities.
Felix Poppelaars +10 more
openaire +1 more source
Interaction of factor H-related proteins FHR-3 and FHR-4 with the third component of complement
Molecular Immunology, 1998J. Hellwage +4 more
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Functional comparison of human factor H-related protein 4 (FHR-4) isoforms
Molecular Immunology, 2007Michael Mihlan +2 more
openaire +1 more source
Factor H-related protein 4 (FHR-4) interacts with C-reactive protein in vitro and in vivo
Molecular Immunology, 2007Michael Mihlan +3 more
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