Results 61 to 70 of about 356 (134)

FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation [PDF]

, 2017
Factor H–related protein (FHR) 1 is one of the five human FHRs that share sequence and structural homology with the alternative pathway complement inhibitor FH.
Zsóka Szabó, Susan M. Lea, Joseph J. E. Caesar, Barbara Uzonyi, Marcell Cserhalmi, Mihály Józsi, Zoltán Prohászka, Zsófia Bánlaki, Agustín Tortajada, T. Sakari Jokiranta, Éva Kárpáti, Ádám I. Csincsi, Santiago Rodríguez de Córdoba   +12 more
core   +1 more source

STRUCTURAL AND FUNCTIONAL ANALYSIS OF COMPLEMENT FACTOR H: A CRUCIAL PROTEIN IN SEVERAL DISORDERS [PDF]

, 2015
Il Fattore H del complemento (FH) è un importante regolatore della via alternativa del complemento: protegge infatti le cellule dell’ospite dall’attacco del sistema del complemento e carenze di FH sia qualitative e quantitative dovute a mutazioni nel ...
S. Berra
core   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Caracterización funcional y estructural de la proteína Factor H-related B (FHR-B) del sistema del complemento del ratón

, 2022
Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Químicas, leída el 05-05-2022La existencia de proteínas relacionadas con el factor H (FHR) en el ratón se conoce desde hace algún tiempo, pero aún no está claro su equivalencia ...
Martín-Ambrosio Doménech, Adrián
core  

Poster Session 3

Pregnancy, Volume 2, Issue S1, January 2026.
wiley   +1 more source

Poster Session 4

Pregnancy, Volume 2, Issue S1, January 2026.
wiley   +1 more source

A Novel Atypical Hemolytic Uremic Syndrome-Associated Hybrid CFHR1CFH Gene Encoding a Fusion Protein That Antagonizes Factor H-Dependent Complement Regulation

, 2015
Genomic aberrations affecting the genes encoding factor H (FH) and the five FH-related proteins (FHRs) have been described in patients with atypical hemolytic uremic syndrome (aHUS), a rare condition characterized by microangiopathic hemolytic anemia ...
Valoti, Elisabetta, Tortajada Alonso, Agustín, Noris, Marina   +2 more
core   +2 more sources

Poster Session 1

Pregnancy, Volume 2, Issue S1, January 2026.
wiley   +1 more source

Complement Factor H-Related Proteins FHR1 and FHR5 Interact With Extracellular Matrix Ligands, Reduce Factor H Regulatory Activity and Enhance Complement Activation

Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglichThis publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (
Blom, Anna M, Ferreira, Viviana P, Papp, Alexandra, Szábo, Zsóka, Bánlaki, Zsófia, Papp, Krisztián, Cserhalmi, Marcell, Csincsi, Ádám I, Ermert, David, Prohászka, Zoltán, Józsi, Mihály, Uzonyi, Barbara, Erdei, Anna   +12 more
core   +1 more source

Use of a Monoclonal antibody (5H5) recognizing FH but not FHL-1 and FHRs to study FH in aHUS patients

, 2015
Factor H (FH) is a negative regulator of Complement that protects host cells from complement attack. Deficiencies due to mutations in the CFH gene are frequently associated with a number of human diseases, such as membranoproliferative glomerulonephritis
S. Salardi, S. Berra, A. Clivio, G. Ardissimo, M. Cugno, S. Tedeschi   +5 more
core   +1 more source