Results 51 to 60 of about 356 (134)

Expression and Immunogenicity Analysis of Recombinant Leptospira Interrogans Surface Protein LigA in Mouse Model

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Implemented strategies in designing, production, purification and immunogenicity of the recombinant Leptospiral immunoglobulin‐like surface protein‐A (r‐Lig A) as a vaccine candidate. ABSTRACT Background Pathogenic strains of spirochetes of Leptospira spp. cause a globally distributed zoonotic disease called leptospirosis.
Aida Chalesh, Pejvak Khaki, Soheila Moradi Bidhendi, Majid Tebianian, Morteza Taghizadeh Tarnabi   +4 more
wiley   +1 more source

Pulmonary Hypertension: Molecular Mechanisms and Clinical Studies

MedComm, Volume 6, Issue 3, March 2025.
The figure highlights the interplay of genetic and epigenetic mechanisms in pulmonary hypertension (PH) and their implications for therapeutic strategies. The genetic mechanism section features key genes implicated in PH pathogenesis. The epigenetic mechanism encompasses DNA methylation, RNA methylation, noncoding RNAs (miRNA, lncRNA), and histone ...
Joseph Adu‐Amankwaah, Qiang You, Xiaoer Liu, Jiayi Jiang, Dongqi Yang, Kuntao Liu, Jinxiang Yuan, Yanfang Wang, Qinghua Hu, Rubin Tan   +9 more
wiley   +1 more source

Human factor H-related protein 5 (FHR-5). A new complement-associated protein.

The Journal of biological chemistry, 2001
A novel human plasma protein has been identified as a universal component of complement deposits, when complement is detected immunohistochemically in vivo. The protein is homologous to complement factor H and related proteins and has been designated factor H-related protein 5 (FHR-5).
J L, McRae, P J, Cowan, D A, Power, K I, Mitchelhill, B E, Kemp, B P, Morgan, B F, Murphy   +6 more
openaire   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +2 more sources

image_1_Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4.PDF

, 2018
Recent research has elucidated circulating levels of almost all factor H-related (FHR) proteins. Some of these proteins are hypothesized to act as antagonists of the important complement regulator factor H (FH), fine-tuning complement regulation on human
Taco W. Kuijpers (194739), Richard B. Pouw (2578096), Mihály Józsi (345845), Mieke C. Brouwer (2578099), Diana Wouters (369450), Anna E. van Beek (5106254)   +5 more
core   +1 more source

The Human Factor H-related Protein 4 (FHR-4) [PDF]

Journal of Biological Chemistry, 1997
Christine Skerka, Jens Hellwage, Wilfried Weber, Anne Tilkorn, Friedrich Buck, Thomas Marti, Eva Kampen, Ulrike Beisiegel, Peter F. Zipfel   +8 more
openaire   +1 more source

Contribución del fh y las proteínas FHRs del complemento en la predisposición y evolución del Síndrome Hemolítico-Urémico atípico y la nefropatía por IgA [PDF]

, 2022
Tesis Doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Bioquímica. Fecha de Lectura: 09-09-2022El Síndrome Hemolítico Urémico atípico (SHUa) y la Nefropatía por IgA (NIgA) son enfermedades renales con una
Gómez Delgado, Irene Isabel
core  

Human Factor H-related Protein 5 (FHR-5) [PDF]

Journal of Biological Chemistry, 2001
Jennifer L. McRae, Peter J. Cowan, David A. Power, Ken I. Mitchelhill, Bruce E. Kemp, B. Paul Morgan, Brendan F. Murphy   +6 more
openaire   +1 more source

The human factor H-related protein 4 (FHR-4). A novel short consensus repeat-containing protein is associated with human triglyceride-rich lipoproteins.

The Journal of biological chemistry, 1997
A novel apoprotein of an apparent molecular mass of 86 kDa in its unreduced form was identified in human triglyceride-rich lipoproteins. This protein was purified and the amino acid sequence of six proteolytic fragments was found to overlap with that of the factor H-related proteins. In parallel we identified the cDNA encoding a new complement factor H-
C, Skerka, J, Hellwage, W, Weber, A, Tilkorn, F, Buck, T, Marti, E, Kampen, U, Beisiegel, P F, Zipfel   +8 more
openaire   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source