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Factor H autoantibodies in membranoproliferative glomerulonephritis
Molecular Immunology, 2012Factor H autoantibodies are found in ~10% of aHUS patients. Most are associated with complete deficiency of factor H related proteins 1/3 and bind to the C terminal recognition domain. MPGN, like aHUS, is characterised by complement activation. In this study we, therefore, examined the hypothesis that factor H autoantibodies are associated with MPGN ...
Goodship THJ +18 more
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Complement Factor H: Physiology and Pathophysiology
Seminars in Thrombosis and Hemostasis, 2001The human plasma protein factor H, which is a multifunctional, multidomain protein, acts as a central regulator of the complement system. In addition to its complement regulatory activities, factor H has multiple physiological activities and 1) acts as an extracellular matrix component, 2) binds to cellular receptors of the integrin type, and 3 ...
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The Pleiotropy of Complement Factor H
JAMA Ophthalmology, 2023Elizabeth J, Rossin, Lucia, Sobrin
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A radiation hybrid map of complement factor H and factor H-related genes
Immunogenetics, 1999M A, Díaz-Guillén +2 more
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Evolving standards of care and new challenges in the management of HER2‐positive breast cancer
Ca-A Cancer Journal for Clinicians, 2020Grace M Choong +2 more
exaly
Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
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Treatment of renal cell carcinoma: Current status and future directions
Ca-A Cancer Journal for Clinicians, 2017Pedro Coelho Barata, Brian I Rini
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