Results 11 to 20 of about 256,760 (210)
Thrombosis Journal, 2023 Background Anti-factor Xa assays and activated partial thromboplastin time (aPTT) are mainly employed to monitor patients treated with heparins. According to the Clinical and Laboratory Standards Institute and the French Working Group on Haemostasis and ...
Marion Gremillet +3 more
doaj +1 more source
The spatial temporal regime of stream flow of the conterminous U.S. in connection with indices of global atmospheric circulation [PDF]
, 2007 Long-term stream flow records (1929-1988) from seventy one U.S. Geological Survey gauging stations with drainage area in range 1000-10000 sq mi were analyzed using multivariate statistics. Factor analysis of average annual flow revealed seven patterns of
Boris Shmagin +2 more
core +2 more sources
Haematologica, 2014 Vitamin K-dependent proteases generated in response to vascular injury and infection enable fibrin clot formation, but also trigger distinct immuno-regulatory signaling pathways on myeloid cells.
Eimear M. Gleeson +6 more
doaj +1 more source
Frontiers in Pediatrics, 2021 Objective: The optimal management of anticoagulation in neonatal/pediatric patients during extracorporeal membrane oxygenation (ECMO) has not been established yet and varies greatly among ECMO centers worldwide.
Alba Perez Ortiz +7 more
doaj +1 more source
Multidimensional Analysis of Snow Cover Data in South Dakota Diversity of Landscapes [PDF]
, 2008 Snow distribution in SD was studied with Factor Analysis (FA) of monthly total snowfall [in]. The long-term data obtained from the High Plains Regional Climate Center were used for the territory of South Dakota.
Boris Shmagin, Carol Johnston
core +2 more sources
Gla-domainless factor Xa: molecular bait to bypass a blocked tenase complex
Haematologica, 2012 Background Hemophilia is caused by deficiencies in coagulation factor VIII or IX, resulting in direct blockade of the intrinsic tenase complex and indirect blockade of the extrinsic tenase complex which is rapidly inhibited upon binding of factor Xa to ...
Raphaël Marlu, Benoît Polack
doaj +1 more source
Heavy menstrual bleeding on direct factor Xa inhibitors: Rationale and design of the MEDEA study
Research and Practice in Thrombosis and Haemostasis, 2021 Background In premenopausal women, treatment with direct oral factor Xa inhibitors is associated with an increased risk of heavy menstrual bleeding (HMB) compared with vitamin K antagonists (VKA).
Eva N. Hamulyák +18 more
doaj +1 more source
Discovery and development of Factor Xa inhibitors (2015–2022)
Frontiers in Pharmacology, 2023 As a pathological coagulation process, thrombus can lead to many serious diseases, including ischemic stroke, acute myocardial infarction (AMI), acute coronary syndrome (ACS), and deep venous thrombosis (DVT).
Wei Zheng +5 more
doaj +1 more source
TH Open, 2018 Rivaroxaban and apixaban are both small molecules that reversibly inhibit factor Xa. Compared with rivaroxaban, apixaban has minimal effects on the prothrombin time and activated partial thromboplastin time.
Paul Y. Kim +7 more
doaj +1 more source
Establishment of prophylactic enoxaparin dosing recommendations to achieve targeted anti-factor Xa concentrations in children with CHD [PDF]
, 2018 Background Enoxaparin may be used to prevent central venous catheter-related thrombosis in patients with CHD. We aimed to determine whether current enoxaparin dosing regimens effectively achieve anti-factor Xa concentrations within prophylactic goal ...
Israel, Emily N. +2 more
core +1 more source