Results 21 to 30 of about 40,684 (247)
Evolutionary dynamics on a regular networked structured and unstructured multi‐population
International Journal of Robust and Nonlinear Control, EarlyView., 2023 Abstract In this paper, we study collective decision‐making in a multi‐population framework, where groups of individuals represent whole populations that interact by means of a regular network. Each group consists of a number of players and every player can choose between two options.
Wouter Baar +2 more
wiley +1 more source
Oral Direct Factor Xa Inhibitors [PDF]
Circulation Research, 2012 Vitamin K antagonists, such as warfarin, have been the mainstay of oral anticoagulation for many decades. Although effective, warfarin has numerous limitations, including a variable dose requirement from patient to patient because of differences in dietary vitamin K intake, common genetic polymorphisms, and multiple drug interactions that affect its ...
Calvin H, Yeh +2 more
openaire +2 more sources
Advanced Science, EarlyView.A high‐entropy air electrode material, Gd0.2Pr0.2Ba0.2Sr0.2Ca0.2FeO3−δ (GPBSCF), is developed for both solid oxide fuel cells and reversible protonic ceramic cells. Its enhanced activity stems from increased oxygen vacancies/holes. The stability improvement is attributed to lattice distortion, while thermal expansion reduction is synergistically due to
Ying Zhang +9 more
wiley +1 more source
Mapping of the factor Xa-binding site on factor Va by site-directed mutagenesis.
, 2008 Activated coagulation factor V functions as a cofactor to factor Xa in the conversion of prothrombin to thrombin. Based on introduction of extra carbohydrate side chains in recombinant factor V, we recently proposed several regions in factor Va to be ...
Dahlbäck, Björn +5 more
core +1 more source
Advanced Science, EarlyView.Increasing nanocurvature effectively enriches the local electron density of the M–N4 motif, which facilitates electron transfer from the metal center to nitrogen atoms. This electronic behavior intensifies the localization and asymmetric distribution of charge, thereby significantly amplifying the dipole moment and polarizability.
Daohu Sheng +7 more
wiley +1 more source
Recombinant Tissue Factor Pathway Inhibitor Enhances the Binding of Factor Xa to Human Monocytes
, 2001 SummaryTissue factor pathway inhibitor (TFPI) is a kunitz-type inhibitor of activated factor X (Xa). TFPI was reported to mediate Xa binding to a few of carcinoma cell lines.
Fletcher Taylor +4 more
core +1 more source
Advanced Science, EarlyView.A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni +10 more
wiley +1 more source
, 2003 The specific Kunitz Bauhinia ungulata factor Xa inhibitor (BuXI) and the Bauhinia variegata trypsin inhibitor (BvTI) blocked the activity of trypsin, chymotrypsin, plasmin, plasma kallikrein and factor XIIa, and factor Xa inhibition was achieved only by ...
Pott, V. J. +7 more
core +1 more source
Roles of factor Xa beyond coagulation [PDF]
Journal of Thrombosis and Thrombolysis, 2021 AbstractOral anticoagulant therapy has changed by clinical evidence that coagulation factor Xa (FXa) can be safely and effectively targeted for thromboprophylaxis. Because thrombotic and thrombo-inflammatory diseases are frequently caused by excessive activation of the tissue factor (TF) pathway, activation of FX by the TF-FVIIa complex is of central ...
openaire +4 more sources
Advanced Science, EarlyView.By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang +13 more
wiley +1 more source