Results 41 to 50 of about 4,372,209 (230)

Anion Engineering of Surface Frustrated Lewis Pairs for Light‐Assisted CO2 Hydrogenation to Methanol

Angewandte Chemie, EarlyView.
Anion engineering through nitrogen incorporation regulates the local coordination environment and promotes the formation of defect‐associated Ga–O/N frustrated Lewis pairs in non‐stoichiometric zinc gallium oxide. The engineered surface sites facilitate heterolytic H2 splitting, while the modified electronic structure enhances light utilization ...
Rui Song, Jiuli Guo, Chaoqian Ai, Xueqiu Wu, Andrew Wang, Yang‐Fan Xu, Chaoran Li, Zhijie Chen, Paul N. Duchesne, Emerson MacNeil, Zeshu Zhang, Jianheng Xu, Jingyan Zhang, Yahan Zhang, Xiaoliang Yan, Xingda An, Wenqiang Qu, Yiran Li, Guangming Cai, Zhihao Zhu, Jessica Ye, Athanasios A. Tountas, Wenzhe Zhou, Maochang Liu, Chandra Veer Singh, Le He, Dengwei Jing, Geoffrey A. Ozin   +27 more
wiley   +2 more sources

The discovery of rivaroxaban: translating preclinical assessments into clinical practice

Frontiers in Pharmacology, 2013
Direct oral anticoagulants that target a single coagulation factor (such as factor Xa or thrombin) have been developed in recent years in an attempt to address some of the limitations of traditional anticoagulants.
Dagmar eKubitza, Elisabeth ePerzborn, Scott D Berkowitz   +2 more
doaj   +1 more source

Lithium‐Ion Battery Safety Evaluation by Quantifying Lithium Plating Degree Based on Pressure Signals

Advanced Science, EarlyView.
Low N/P cells enable controllable lithium plating, allowing the lithium plating degree (DLi) to be quantified and linked to thermal safety. Pressure signals during calibration provide a non‐destructive route to diagnose DLi, while thermal response tests define safety levels and management strategies. The framework remains applicable in commercial 12 Ah
Haonan Liu, Jiangong Zhu, Wenyuan Weng, Bin Shen, Wenjun Fan, Yang Wang, Huapeng Lu, Wuliyasu He, Chunjing Lin, Xuezhe Wei, Haifeng Dai   +10 more
wiley   +1 more source

Intracranial hemorrhage in patient treated with rivaroxaban

Hematology Reports, 2014
Rivaroxaban is an oral factor Xa inhibitor used for stroke prevention in atrial fibrillation. There are currently no evidence-based guidelines for the treatment of hemorrhagic side effects of factor Xa inhibitors.
Michelle Molina, Virany H. Hillard, Robert Fekete   +2 more
doaj   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Daboxin P, a Major Phospholipase A2 Enzyme from the Indian Daboia russelii russelii Venom Targets Factor X and Factor Xa for Its Anticoagulant Activity. [PDF]

PLoS ONE, 2016
In the present study a major protein has been purified from the venom of Indian Daboia russelii russelii using gel filtration, ion exchange and Rp-HPLC techniques.
Maitreyee Sharma, Janaki Krishnamurthy Iyer, Norrapat Shih, Munmi Majumder, Venkata Satish Kumar Mattaparthi, Rupak Mukhopadhyay, Robin Doley   +6 more
doaj   +1 more source

Inhibition of factor Xa and trypsin by tetrapeptide inhibitors.

, 2013
Inhibition of factor Xa and trypsin by tetrapeptide inhibitors.
Sheuli Zakia (328736), Pedro J. B. Pereira (116034), Julian Gingold (328737), Ana C. Figueiredo (328735), Manfred Philipp (328738), Cristina C. Clement (251207)   +5 more
core   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Variation in coagulation factor activity levels cause discrepancies between activated partial thromboplastin time and anti-Xa activity for heparin monitoring: a retrospective observational study

Journal of Intensive Care, 2023
Background Unfractionated heparin (UFH) is primarily monitored using activated partial thromboplastin time (APTT). However, the recent introduction of anti-activated factor X (anti-Xa) activity testing has provided a direct evaluation of Xa inhibition by
Tomoyo Saito, Mineji Hayakawa, Osamu Kumano, Yoshinori Honma, Mone Murashita, Jun Kato, Syouki Fukui, Masaki Takahashi, Yuki Takahashi, Takumi Tsuchida, Asumi Mizugaki, Shuhei Takauji, Mariko Hayamizu, Tomonao Yoshida, Kenichi Katabami, Takeshi Wada, Kunihiko Maekawa   +16 more
doaj   +1 more source

Thrombin and factor Xa cleave madanin-1 and madanin-2.

, 2013
Thrombin and factor Xa cleave madanin-1 and madanin-2.
Pedro José Barbosa Pereira (60152), Ana C. Figueiredo (328735), Daniele de Sanctis (444597)   +2 more
core   +1 more source