Effect of a single Dialysis session on plasma Lp(a) levels in patients on Maintenance haemodialysis [PDF]
Background: Cardiovascular disease (CVD) is a major cause of mortality in End stage renal disease (ESRD) patients on Maintenance haemodialysis (MHD).
Aparna R. Bitla +5 more
core +1 more source
Azadirachta indica induced suppression of Mycobacterium tuberculosis secreted proteins in human monocyte [PDF]
The H37Rv strain of MTB was grown in modified Sauton’s medium till mid-log phase. Peripheral blood mononuclear cells (PBMC) were isolated by density gradient sedimentation on Ficoll-Paque separation medium.
Ajay Kumar, Jawed Iqbal, Najmul Islam
core +2 more sources
Factor Xa or thrombin: is factor Xa a better target? [PDF]
Existing vitamin K antagonists (VKAs) have drawbacks that limit their effectiveness, safety, and overall frequency of use. Oral anticoagulants in development with targeted action against individual coagulation factors, specifically direct factor (F) Xa and IIa inhibitors, appear to have pharmacokinetic and pharmacodynamic properties that overcome the ...
openaire +2 more sources
Intracranial hemorrhage in patient treated with rivaroxaban
Rivaroxaban is an oral factor Xa inhibitor used for stroke prevention in atrial fibrillation. There are currently no evidence-based guidelines for the treatment of hemorrhagic side effects of factor Xa inhibitors.
Michelle Molina +2 more
doaj +1 more source
Slug-based epithelial-mesenchymal transition gene signature is associated with prolonged time to recurrence in glioblastoma [PDF]
Background We previously identified a precise stage-associated gene expression signature of coordinately expressed genes, including the transcription factor Slug (SNAI2) and other epithelial mesenchymal transition (EMT) markers, present in ...
Darrell J. Yamashiro +4 more
core +1 more source
Metagenomic study of the human skin microbiome associated with acne [PDF]
The human microbiota contributes to our normal postnatal development and plays a significant role in defining our physiology. To understand the role of microbiota in human health and disease, we study the skin microbiome in pilosebaceous units (hair ...
Huiying Li
core +2 more sources
Daboxin P, a Major Phospholipase A2 Enzyme from the Indian Daboia russelii russelii Venom Targets Factor X and Factor Xa for Its Anticoagulant Activity. [PDF]
In the present study a major protein has been purified from the venom of Indian Daboia russelii russelii using gel filtration, ion exchange and Rp-HPLC techniques.
Maitreyee Sharma +6 more
doaj +1 more source
Pregnancy Obstructs Involution Stage II of the Mammary Gland in Cows: General Biological Implications [PDF]
*Background* Repeated research findings over the last 4 decades show that involution of mammary glands in dairy cows did not regress to same extend as that noticed in other mammalian species. *Methodology/Principal Findings ...
Ana-Maria Anug +3 more
core +1 more source
Biological networks and epistasis in genome-wide association studies [PDF]
Over the last few years, technological improvements have made possible the genotyping of hundreds of thousands of SNPs, enabling whole-genome association studies.
Leif Schauser +3 more
core +3 more sources
Background Unfractionated heparin (UFH) is primarily monitored using activated partial thromboplastin time (APTT). However, the recent introduction of anti-activated factor X (anti-Xa) activity testing has provided a direct evaluation of Xa inhibition by
Tomoyo Saito +16 more
doaj +1 more source

