Results 51 to 60 of about 40,684 (247)

Factor Xa stimulates fibroblast procollagen production, proliferation, and calcium signaling via PAR1 activation

, 2005
Fibroblast proliferation and procollagen production are central features of tissue repair and fibrosis. In addition to its role in blood clotting, the coagulation cascade proteinase thrombin can contribute to tissue repair by stimulating fibroblasts via ...
Blanc-Brude, Olivier P., Leoni, Patricia, Chambers, Rachel C., Archer, Fabienne, Bolsover, Steven, Laurent, Geoffrey J., Derian, Claudia   +6 more
core   +1 more source

Extent, characteristics and policy applications of Key Biodiversity Areas

Biological Reviews, EarlyView.
ABSTRACT A global standard for the identification of Key Biodiversity Areas (KBAs) was published 10 years ago to provide a unified set of criteria for identifying ‘sites of significance for the global persistence of biodiversity’. We review the initiative's origins, the KBA identification process, characteristics of the current network, threats, policy
Stuart H. M. Butchart, Olivia Crowe, Tom Scott, Andrew J. Plumptre, Megan Eldred, Ellen McKee, Zoltan Waliczky, Ibrahim Al Hasani, Adrián B. Azpiroz, Daniele Baisero, Fred Barasa, Alison E. Beresford, Bezeng S. Bezeng, Charlotte Boyd, Thomas M. Brooks, Graeme Buchanan, Gill Bunting, Sofia Capellan, Neil Cox, Tim R. B. Davenport, Tammy E. Davies, Gina Della Togna, Wendy Elliott, Matt Foster, Jo Gilbert, Jonathan M. Handley, Diego Juffe‐Bignoli, Victoria R. Jones, Naomi Kingston, Jeannot Kivono, John Lamoreux, Penny F. Langhammer, James Lewis, Bruce Liggitt, Daniel Marnewick, Paul Matiku, Erin McCreless, Rachel A. Neugarten, Catherine Numa, Mark O'Brien, Madhu Rao, Ciara Raudsepp‐Hearne, Justina C. Ray, Samridhi Rijal, Jon Paul Rodríguez, Jurgis Sapijanskas, Wes Sechrest, Martin Sneary, Andrew Snyder, Konstantina Spiliopoulou, Thomas Starnes, Cecilia Tobar, Gautam Surya, Marcelo F. Tognelli, Andrew W. Tordoff, Maria G. Toscano, Yongyut Trisurat, Amy Upgren   +57 more
wiley   +1 more source

Supratherapeutic anti-factor Xa levels in patients receiving prophylactic doses of enoxaparin: A case series

, 2016
IntroductionEnoxaparin prophylaxis prevents venous thromboembolism in surgical patients. Real time anti-Factor Xa monitoring for surgical patients on enoxaparin prophylaxis is increasingly common.Presentation of casesWe report on three cancer patients ...
Prazak, Ann Marie, Varghese, Thomas K., Pannucci, Christopher J., Graves, Kencee K.   +3 more
core   +1 more source

Coagulation Factor Xa

, 2013
The third edition of the Handbook of Proteolytic Enzymes aims to be a comprehensive reference work for the enzymes that cleave proteins and peptides, and contains over 800 chapters. Each chapter is organized into sections describing the name and history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing
Brown, Mark A., Stenberg, Leisa M., Stenflo, Johan   +2 more
openaire   +1 more source

Consumer Mobile Phone Recycling Behaviour: A Systematic Review and Future Research Agenda

Journal of Consumer Behaviour, EarlyView.
ABSTRACT Mobile phone recycling has received increasing attention from scholars and practitioners due to its environmental, social, and economic impacts. However, knowledge about consumer mobile phone (MP) recycling behaviour is fragmented, making it challenging to develop effective strategies to promote this behaviour. This study follows the Preferred
Xinru (Angie) Jiang, Ninh Nguyen, Steven Greenland, Jacqueline K. Eastman, Chrystie Watson   +4 more
wiley   +1 more source

Inhibition of human blood coagulation factor Xa by alpha 2-macroglobulin

, 1987
The inactivation of activated factor X (factor Xa) by alpha 2-macroglobulin (alpha 2M) was studied. The second-order rate constant for the reaction was 1.4 X 10(3) M-1 s-1. The binding ratio was found to be 2 mol of factor Xa/mol of alpha 2M. Interaction
Meijers, J. C., Bouma, B. N., Tijburg, P. N.   +2 more
core   +1 more source

High Entropy–Driven Performance Enhancement in Perovskite Oxides for Energy Conversion and Storage Systems

Carbon Energy, EarlyView.
High‐entropy perovskite oxides enable tunable structures and properties through multi‐cation disorder and entropy stabilization. This review summarizes advances in synthesis, structural and defect engineering, and their applications in OER/ORR, CO2RR, and electrochemical energy storage, highlighting in situ characterization and modeling that clarify ...
Obeylaw Moyo, Jiaqiao Yang, Mingzhuang Liang, Hyunseung Kim, Wei Wang, Yong Beom Kim, Junxiong Zhang, WooChul Jung, Hainan Sun   +8 more
wiley   +1 more source

Dinuclear Copper(I) Complexes Featuring Metal–Metal Interactions and a μ2‐Bridging Phosphane With Additional Olefinic Binding Sites

Chemistry – A European Journal, EarlyView.
A Cu2P triangle captured in a tetrapodal phosphane tris(olefin) ligand, where all binding forces are weak apart from the Cu─P interaction. ABSTRACT The molecule Ptrop3 contains in each trop unit (trop = dibenzo[a,d]cyclohepten‐5‐yl) a rigid central seven‐membered ring with an olefinic binding site making Ptrop3 potentially a tetradentate ligand ...
Zhongshu Li, Daniel Himmelbauer, Jan Oswald, Michael Wörle, René Verel, Zoltán Benkő, Hansjörg Grützmacher   +6 more
wiley   +1 more source

Coagulant factor Xa inhibits prostacyclin formation in human endothelial cells. Role of factor V.

, 1985
Thrombin stimulates prostacyclin formation in cultured human endothelial cells. However, a countervailing process that prevents prostacyclin overproduction has not been described previously.
R W Colman, H C Chiu, G J Stewart, A K Sinha, A K Dutta-Roy   +4 more
core   +1 more source

The new factor Xa inhibitor: Apixaban

Journal of Pharmacology and Pharmacotherapeutics, 2014
Cardiovascular diseases are still the most important cause of morbidity and mortality worldwide and anti-thrombotic treatment is widely used as a result. The currently used drugs include heparin and its derivatives, vitamin K antagonists, though efficacious, have their own set of limitations like unpredictable pharmacokinetic profile, parenteral route (
Bhanwra, Sangeeta, Ahluwalia, Kaza
openaire   +3 more sources