Results 91 to 100 of about 788,607 (367)
Designing Direct and Indirect Factor Xa Inhibitors [PDF]
, 2012 Anticoagulants are the basis for treatment and prevention of thrombotic diseases. The currently available medicines are associated with a wide range of adverse reactions that mandates developing new anticoagulants.
Al-Horani, Rami
core +1 more source
How we treat bleeding associated with direct oral anticoagulants [PDF]
, 2016 Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo +4 more
core +1 more source
Spintronic Memtransistor Leaky Integrate and Fire Neuron for Spiking Neural Networks
Advanced Electronic Materials, EarlyView.Spintronic memtransistor neurons based on domain walls enable energy‐efficient, field‐gated, and current‐controlled LIF functionality for neuromorphic computing, as demonstrated. When integrated into spiking neural network architectures, these devices achieve >96% pattern recognition accuracy, demonstrating high performance, scalability, and mem ...
Aijaz H. Lone +7 more
wiley +1 more source
Hard x-ray spectroscopy in NaxCoO2 and superconducting NaxCoO2 - yH2O: A view on the bulk Co electronic properties [PDF]
, 2006 The electronic properties of Co in bulk Na0.7CoO2 and the superconducting hydrated compound Na0.35CoO2 - y H2O have been investigated by x-ray absorption spectroscopy (XAS) and resonant inelastic x-ray scattering (RIXS) using hard x-rays. The XAS spectra at the Co K-edge were measured in both compounds with two different polarization directions.
arxiv +1 more source
Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy
Journal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023 Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone +12 more
wiley +1 more source
The Quasar Main Sequence explained by the combination of Eddington ratio, metallicity and orientation [PDF]
, 2019 We address the effect of orientation of the accretion disk plane and the geometry of the broad-line region (BLR) as part of an effort to understand the distribution of quasars in the optical plane of the quasar main sequence. We utilize the photoionization code CLOUDY to model the BLR incorporating the grossly underestimated form factor ($f$). Treating
arxiv +1 more source
Structural insights into characterizing binding sites in EGFR kinase mutants [PDF]
Journal of Chemical Information and Modeling, 2018, 2018 Over the last two decades epidermal growth factor receptor (EGFR) kinase has become an important target to treat non-small cell lung cancer (NSCLC). Currently, three generations of EGFR kinase-targeted small molecule drugs have been FDA approved. They nominally produce a response at the start of treatment and lead to a substantial survival benefit for ...
arxiv +1 more source
Thrombin Inhibitors from Different Animals [PDF]
, 2010 Venous and arterial thromboembolic diseases are still the most frequent causes of death and disability in high-income countries. Clinical anticoagulants are inhibitors of enzymes involved in the coagulation pathway, such as thrombin and factor Xa ...
Morais-Zani, K. +3 more
core +4 more sources
Annals of Neurology, EarlyView.Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius +11 more
wiley +1 more source
Green open access in computer science - an exploratory study on author-based self-archiving awareness, practice, and inhibitors [PDF]
, 2015 Access to the work of others is something that is too often taken for granted, yet problematic and difficult to be obtained unless someone pays for it. Green and gold open access are claimed to be a solution to this problem. While open access is gaining momentum in some fields, there is a limited and seasoned knowledge about self-archiving in computer ...
arxiv +1 more source