Results 21 to 30 of about 34,813 (259)

Global cerebral infarction after aortic arch replacement surgery in a patient with postoperatively revealed factor XII deficiency: a case report

Journal of Medical Case Reports, 2020
Background This case report presents a case of a patient with global cerebral infarction of uncertain etiology following an emergency surgery for acute type A aortic dissection. As a result, factor XII deficiency was revealed postoperatively.
Keisuke Yoshida, Shiori Tanaka, Yuki Sato, Kazuhiro Watanabe, Kenichi Muramatsu, Masahiro Murakawa   +5 more
doaj   +1 more source

Factor XII (Hageman) Levels in Women with Recurrent Pregnancy Loss

Journal of Pregnancy, 2014
Objective. To evaluate factor XII levels in women with recurrent pregnancy loss (RPL) in a tertiary referral hospital. Methods. Women who were referred to our hospital for two consecutive abortions or three abortions in between 2007 and 2013 were ...
A. Seval Ozgu-Erdinc, Cihan Togrul, Ayla Aktulay, Umran Buyukkagnici, Elif Gul Yapar Eyi, Salim Erkaya   +5 more
doaj   +1 more source

Impact of Deficiency of Intrinsic Coagulation Factors XI and XII on Ex Vivo Thrombus Formation and Clot Lysis

TH Open, 2019
The contributions of coagulation factor XI (FXI) and FXII to human clot formation is not fully known. Patients with deficiency in FXI have a variable mild bleeding risk, whereas FXII deficiency is not associated with bleeding.
José W. P. Govers-Riemslag, Joke Konings, Judith M. E. M. Cosemans, Johanna P. van Geffen, Bas de Laat, Johan W. M. Heemskerk, Yesim Dargaud, Hugo ten Cate   +7 more
doaj   +1 more source

The contact system proteases play disparate roles in streptococcal sepsis

Haematologica, 2020
Sepsis causes an activation of the human contact system, an inflammatory response mechanism against foreign surfaces, proteins and pathogens. The serine proteases of the contact system, factor XII and plasma kallikrein, are decreased in plasma of septic ...
Juliane Köhler, Claudia Maletzki, Dirk Koczan, Marcus Frank, Carolin Trepesch, Alexey S. Revenko, Jeffrey R. Crosby, A. Robert Macleod, Stefan Mikkat, Sonja Oehmcke-Hecht   +9 more
doaj   +1 more source

Evaluation of Factor XII Activity in Women with Recurrent Miscarriages

Bezmiâlem Science, 2018
Objective:Our aim is to evaluate factor XII activity in women with recurrent miscarriages by active partial thromboplastin time (aPTT) measurement.Methods:This study was conducted in 145 patients admitted to our clinic with recurrent miscarriages between
Nilay KARACA, Lebriz Hale AKTÜN
doaj   +1 more source

Inflammation and Coagulation are Two Interconnected Pathophysiological Pathways in Atrial Fibrillation Pathogenesis

Journal of Inflammation Research, 2023
Lusine Hazarapetyan,1,2 Parounak H Zelveian,2 Svetlana Grigoryan1,2 1Department of Cardiology, Yerevan State Medical University Named After M. Heratsi, Yerevan, Armenia; 2Scientific Research Institute of Cardiology Named After L Hovhannisyan, Yerevan ...
Hazarapetyan L, Zelveian PH, Grigoryan S
doaj  

Acquired factor XII deficiency in a woman with recurrent pregnancy loss: working on a differential diagnosis in a single case

Journal of Translational Medicine, 2005
Background Antiphospholipid syndrome (APS) has been often associated to RPL since 1980 and some reports in the Literature rarely described antibodies to factor XII in patients with APS.
Di Micco Pierpaolo, De Placido Giuseppe, Ranieri Antonio, Mollo Antonio, Strina Ida, D'Uva Maristella   +5 more
doaj   +1 more source

Anti-Factor XII Autoantibodies in Patients with Recurrent Pregnancy Loss Recognize the Second Epidermal Growth Factor–Like Domain

TH Open, 2019
Summary Background Factor XII (FXII) deficiency and autoantibodies that bind to FXII (anti-FXII) have been described in patients with adverse pregnancy outcomes, including recurrent pregnancy loss.
Yoshihiro Sato, Toshitaka Sugi, Rie Sakai   +2 more
doaj   +1 more source

Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice. [PDF]

PLoS ONE, 2016
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP) suggested that the protease factor XIa contributed to ...
Charles E Bane, Ivan Ivanov, Anton Matafonov, Kelli L Boyd, Qiufang Cheng, Edward R Sherwood, Erik I Tucker, Stephen T Smiley, Owen J T McCarty, Andras Gruber, David Gailani   +10 more
doaj   +1 more source

The prevalence of heterozygous F12 mutations in Chinese population and its relevance to incidents of thrombosis

BMC Medical Genetics, 2018
Background The contribution of moderate coagulation factor XII (FXII) deficiency to development of thromboembolism is still undetermined. We have tried to show the relevance of FXII deficiency to incidences of venous thrombosis by exploring the ...
Xi Wu, Qiulan Ding, Xuefeng Wang, Jing Dai, Wenman Wu   +4 more
doaj   +1 more source