Results 21 to 30 of about 15,476,282 (336)
Blood, 2021 Silasi et al report new data on the role of factor XII in systemic inflammation and pathological coagulation induced by systemic inactivated Staphylococcus aureus in baboons.
R. Silasi +17 more
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Activation of factor XII by dextran sulfate: the basis for an assay of factor XII [PDF]
Blood, 1983 A system was developed for studying the activation of factor XII (Hageman factor) in the presence of dextran sulfate (DS). Salient features of the system included low ionic strength (0.08), low concentration of factor XII (approximately 1/10,000 that in normal plasma), and an excess of exogenous prekallikrein (PK).
D L, Tankersley +2 more
openaire +3 more sources
Medicine Science, 2021 Titanium dioxide (TiO2) nanoparticles are widely used in food, cosmetics, biomedical implants, and pharmaceutical fields. Their effect on blood coagulation in human plasma and blood have been demonstrated.
Evren Kilinc
doaj +1 more source
Factor XII – A Limitation for Divers? [PDF]
Polish Hyperbaric Research, 2015 Abstract The lack of evidence for the tissue-factor dependent activation of the coagulation system and the release of thrombin on one hand, and a decreased concentration of factor XII after short term air, saturated air and heliox exposures, as well as an increased concentration of the plasmin-antiplasmin complex (PAP) after short dives
Olszański, Romuald +3 more
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In vivo roles of factor XII [PDF]
Blood, 2012 AbstractCoagulation factor XII (FXII, Hageman factor, EC = 3.4.21.38) is the zymogen of the serine protease, factor XIIa (FXIIa). FXII is converted to FXIIa through autoactivation induced by “contact” to charged surfaces. FXIIa is of crucial importance for fibrin formation in vitro, but deficiency in the protease is not associated with excessive ...
Thomas, Renné +4 more
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Journal of Neuroanaesthesiology and Critical Care, 2020 Factor XII deficiency is a rare disorder that can complicate the perioperative management of a patient. Factor XII plays an important role in the activation of intrinsic pathway of coagulation; the deficiency, therefore, results in prolongation of ...
Mouleeswaran Sundaram +2 more
doaj +1 more source
Frontiers in Medicine, 2018 Until recently, the role of factor XII (FXII) in hemostasis was not considered to be important since patients with FXII deficiency do not present with bleeding.
Helen V. Wilmot +3 more
doaj +1 more source
Hydrogels by irradiation of a synthetic heparinoid polyelectrolyte [PDF]
, 1983 Gamma irradiation of aqueous solutions of a synthetic heparinoid polyelectrolyte results in the formation of hydrogels, varying in water content and mechanical strength.
Bantjes, A. +5 more
core +4 more sources
Activity of factor XII‐Locarno [PDF]
Research and Practice in Thrombosis and Haemostasis, 2018 Factor XII (FXII) Locarno is a natural variant with proline replacing Arg353 at the activation cleavage site, preventing conversion to the fully active protease factor XIIa (FXIIa). Recently, we showed that FXII restricted to a single chain form (sc-FXII) by replacing Arg353 with alanine expresses proteolytic activity that is enhanced by cofactors such
Mohammed, Bassem M. +4 more
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Frontiers in Cell and Developmental Biology, 2020 As transmitters of biological information, extracellular vesicles (EVs) are crucial for the maintenance of physiological homeostasis, but also contribute to pathological conditions, such as thrombotic disorders.
C. Tripisciano +4 more
semanticscholar +1 more source