Results 111 to 120 of about 21,448 (228)

Leucine‐Restricted Diet Attenuates Small Intestinal Tumorigenesis in ApcMin/+ Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Essential amino acids have been implicated in intestinal physiology and disease, but their individual roles in intestinal tumorigenesis remain unclear. Among the amino acids examined, dietary leucine restriction uniquely suppressed small intestinal tumorigenesis in ApcMin/+ mice.
Yunlong Sui   +11 more
wiley   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

open access: yesInternational Journal of Cancer, Volume 159, Issue 1, Page 144-158, 1 July 2026.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho   +7 more
wiley   +1 more source

Hereditary non-polyposis colorectal carcinoma (HNPCC) : morphological and immunohistochemical studies

open access: yes, 2005
Includes bibliographical references.Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa.
Holm, Hannes
core  

Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications

open access: yesChemistryOpen, Volume 15, Issue 7, July 2026.
Magnetic bead engineering for liquid biopsy diagnostics reviews advances in magnetic bead design for the selective enrichment of circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and extracellular vesicles (EVs) from complex biofluids.
Beatriz Naranjo‐Martínez   +9 more
wiley   +1 more source

Aspartate Transporter SLC1A3 Promotes Colorectal Cancer via MDM2‐p53 Pathway and M2 Macrophage Polarization

open access: yesCancer Science, Volume 117, Issue 7, Page 1813-1827, July 2026.
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng   +9 more
wiley   +1 more source

An immunohistochemical study of beta-catenin in HNPCC colon tumours

open access: yes, 2004
Includes bibliographical references (leaves 49-55).Beta-catenin is normally complexed with adenomatous polyposis coli (APC) protein and E-cadherin adhesion molecule, and localized on the cell membrane.
Watkins, Jennifer G
core  

Investigation of Mutation in a Part of Exon 15 of APC Gene in Patients with Familial Adenomatous Polyposis in Gilan Province

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: Familial adenomatous polyposis (FAP) is a colorectal cancer caused by the mutation in the APC gene, inherited as an autosomal dominant.
M Ahmad Sharbafi, N Ranji
doaj  

How safe is teaching of highly specialized rectal surgery? A propensity score–matched 10‐year cohort study

open access: yesColorectal Disease, Volume 28, Issue 7, July 2026.
Abstract Aim This study aimed to assess the impact of an institutional teaching program of highly specialized rectal procedures on intra‐ and early postoperative outcomes. Methods We performed a retrospective 10‐year cohort study of consecutive patients undergoing low anterior resection (LAR) or abdominoperineal resection (APR) for rectal cancer <12 cm
Simon Cheseaux   +6 more
wiley   +1 more source

Reframing Wnt/β‐Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley   +1 more source

Updated European guidelines for clinical management of familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), gastric adenocarcinoma, proximal polyposis of the stomach (GAPPS) and other rare adenomatous polyposis syndromes: a joint EHTG-ESCP revision [PDF]

open access: yes
European guidelines; Familial adenomatous polyposis; Gastric adenocarcinomaDirectrices europeas; Poliposis adenomatosa familiar; Adenocarcinoma gástricoDirectrius europees; Poliposi adenomatosa familiar; Adenocarcinoma gàstricBackground: Hereditary ...
Bisseling, Tanya   +6 more
core   +1 more source

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