Results 111 to 120 of about 21,448 (228)
Leucine‐Restricted Diet Attenuates Small Intestinal Tumorigenesis in ApcMin/+ Mice
Essential amino acids have been implicated in intestinal physiology and disease, but their individual roles in intestinal tumorigenesis remain unclear. Among the amino acids examined, dietary leucine restriction uniquely suppressed small intestinal tumorigenesis in ApcMin/+ mice.
Yunlong Sui +11 more
wiley +1 more source
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
Includes bibliographical references.Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa.
Holm, Hannes
core
Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications
Magnetic bead engineering for liquid biopsy diagnostics reviews advances in magnetic bead design for the selective enrichment of circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and extracellular vesicles (EVs) from complex biofluids.
Beatriz Naranjo‐Martínez +9 more
wiley +1 more source
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng +9 more
wiley +1 more source
An immunohistochemical study of beta-catenin in HNPCC colon tumours
Includes bibliographical references (leaves 49-55).Beta-catenin is normally complexed with adenomatous polyposis coli (APC) protein and E-cadherin adhesion molecule, and localized on the cell membrane.
Watkins, Jennifer G
core
BACKGROUND AND OBJECTIVE: Familial adenomatous polyposis (FAP) is a colorectal cancer caused by the mutation in the APC gene, inherited as an autosomal dominant.
M Ahmad Sharbafi, N Ranji
doaj
Abstract Aim This study aimed to assess the impact of an institutional teaching program of highly specialized rectal procedures on intra‐ and early postoperative outcomes. Methods We performed a retrospective 10‐year cohort study of consecutive patients undergoing low anterior resection (LAR) or abdominoperineal resection (APR) for rectal cancer <12 cm
Simon Cheseaux +6 more
wiley +1 more source
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley +1 more source
Updated European guidelines for clinical management of familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), gastric adenocarcinoma, proximal polyposis of the stomach (GAPPS) and other rare adenomatous polyposis syndromes: a joint EHTG-ESCP revision [PDF]
European guidelines; Familial adenomatous polyposis; Gastric adenocarcinomaDirectrices europeas; Poliposis adenomatosa familiar; Adenocarcinoma gástricoDirectrius europees; Poliposi adenomatosa familiar; Adenocarcinoma gàstricBackground: Hereditary ...
Bisseling, Tanya +6 more
core +1 more source

