Results 131 to 140 of about 19,814 (246)

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Subclassification of Phenotypic Homozygous Familial Hypercholesterolemia. [PDF]

JACC Asia
Tada H, Harada-Shiba M.
europepmc   +1 more source

Growth Standards for Children With Smith–Magenis Syndrome (SMS)

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 569-578, March 2026.
ABSTRACT Smith–Magenis syndrome (SMS, OMIM 182290) is a complex syndromic diagnosis marked by neurobehavioral differences and distinct facial dysmorphisms, caused by haploinsufficiency of the retinoic acid‐1 (RAI1) gene either by a pathogenic sequence variant or deletion at chromosome 17p11.2 involving a portion or all of this gene.
Julie Hoover‐Fong, John McGready, Leah Fleming, Kerry Schulze, Folami Duncan, Alexis Leonard, Marie Christine de Blois Boucard, Danilo Moretti‐Ferreira, Andrea L. Gropman, Wendy J. Introne, Ann C. M. Smith   +10 more
wiley   +1 more source

Characterization of selected LDLR substitutions in patients with familial hypercholesterolemia. [PDF]

Atheroscler Plus
Targońska M, Janaszak-Jasiecka A, Chmara M, Żuk M, Kalinowski L, Waleron K, Jasiecki J, Wasąg B.   +7 more
europepmc   +1 more source

New Insights Into Changes in the DNA Methylation Pattern of the SHOX Gene in Patients With Léri‐Weill Dyschondrosteosis

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 606-618, March 2026.
ABSTRACT SHOX gene haploinsufficiency is associated with Léri‐Weill dyschondrosteosis (LWD) or idiopathic short stature (ISS) and could be caused by the structural and point mutations in the coding region and by the deletions in SHOX gene regulatory sequences. The role of the duplications in regulatory sequences is ambivalent.
Valeriia Kopytko, Katerina Hirschfeldova, Pavlina Capkova, Roman Solc   +3 more
wiley   +1 more source

Familial hypercholesterolemia [PDF]

, 2011
openaire   +3 more sources

Metformin Ameliorates Cognitive Deficits and Neuroinflammation in a Mouse Model of Familial Hypercholesterolemia. [PDF]

Neurochem Res
do Nascimento NB, Farias HR, Schons T, Padilha APZ, Costa MV, Peres AM, da Silva LDS, Dantas RM, Ramos JMO, Rodrigues MS, Telles F, Guma FTCR, Moreira JCF, Bast RKSS, de Bem AF, de Oliveira J.   +15 more
europepmc   +1 more source

Increased incidence of mild cognitive impairment in long COVID patients

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Though brain fog is common in Long‐coronavirus disease 2019 (Long‐COVID), the incidence of mild cognitive impairment (MCI) is unknown. METHODS In an observational cohort study, recovered COVID‐positive, Long‐COVID, and COVID‐negative subjects underwent blinded evaluation using National Alzheimer's Coordinating Center (NACC) and ...
Jennifer A. Frontera, Arjun V. Masurkar, Rebecca A. Betensky, Zariya Alvarez, Allal Boutajangout, Joshua Chodosh, Salma Hammam, Jessica Hunter, Li Jiang, Melanie Li, Jon Links, Karyn Marsh, Huize Pang, Floyd Silva, Sujata Thawani, Daria Vasilchenko, Alok Vedvyas, Amin Yakubov, Yulin Ge, Thomas Wisniewski   +19 more
wiley   +1 more source

First LDLRAP1 and Recurrent LDLR Mutations in Tunisian Families With Familial Hypercholesterolemia. [PDF]

J Cell Mol Med
Ncir WB, Ben-Mahmoud A, Frikha H, Abdelhedi F, Kacem FH, Majdoub N, Mnif M, Kim HG, Keskes LA, Hottenga JJ.   +9 more
europepmc   +1 more source

Resistance training and subcortical vascular cognitive impairment: A 12‐month randomized trial

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION It is unknown whether progressive resistance training (PRT) improves cognitive function in adults with cerebral small vessel disease and mild cognitive impairment (i.e., subcortical vascular cognitive impairment [SVCI]). METHODS We conducted a 12‐month randomized trial comparing PRT versus balance and tone exercises (BAT) on the ...
Teresa Liu‐Ambrose, Ryan S. Falck, Elizabeth Dao, Rachel A. Crockett, Cindy K. Barha, Narlon C. Boa Sorte Silva, Walid A. Alkeridy, John R. Best, Ging‐Yuek R. Hsiung, Thalia S. Field, Kenneth M. Madden, Jennifer C. Davis, Lisanne F. ten Brinke, Roger C. Tam   +13 more
wiley   +1 more source