Results 141 to 150 of about 52,688 (314)

Study participant impression of use and satisfaction with STS101 (dihydroergotamine nasal powder): Results from the open‐label ASCEND acute migraine study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective/Background This study was undertaken to assess participants' impression of use and satisfaction with STS101 in a long‐term, open‐label safety study. The ASCEND study assessed the safety and tolerability of STS101, an investigational drug–device combination of 5.2 mg dihydroergotamine in a single‐use nasal delivery device for the ...
Jessica Ailani   +4 more
wiley   +1 more source

Older Adults' Self‐Care and Family Caregiver Contribution in Multiple Chronic Conditions: A Dyadic Qualitative Study

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To explore how older adult‐family caregiver dyads jointly manage multiple chronic conditions. Specifically, it investigates how dyads (i) prioritise chronic diseases, (ii) make and negotiate decisions related to self‐care and (iii) define and distribute self‐care tasks and caregiver contributions.
Giulia Andrea Baldan   +6 more
wiley   +1 more source

The causal effects of hypothyroidism on cardiovascular disease: Bidirectional and multivariable Mendelian randomization study

open access: yesJournal of Diabetes Investigation, EarlyView.
Our study suggests bidirectional causal associations between hypothyroidism and both coronary artery disease (CAD) and myocardial infarction (MI). Moreover, hypothyroidism contributes to an increased risk of peripheral atherosclerosis (PAS). ABSTRACT Background Whether hypothyroidism and cardiovascular disease (CVD) are causally related remains ...
Xuan Bai, Mengyi Sun, Xu Han
wiley   +1 more source

Determination of selected oxysterol levels, oxidative stress, and macrophage activation indicators in children and adolescents with familial hypercholesterolemia [PDF]

open access: gold
Erhan Canbay   +14 more
openalex   +1 more source

Structural and Biochemical Characterization of the Wild Type PCSK9-EGF(AB) Complex and Natural Familial Hypercholesterolemia Mutants [PDF]

open access: hybrid, 2008
Matthew J. Bottomley   +17 more
openalex   +1 more source

High cholesterol absorption efficiency interferes with bile acid metabolism and cholesterol elimination from the body

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Elevated low‐density lipoprotein (LDL) cholesterol causes atherosclerotic cardiovascular diseases. Variables of whole‐body cholesterol metabolism, for example, high cholesterol absorption efficiency, might also be atherogenic, whereas the role of bile acids is controversial.
Piia Simonen   +4 more
wiley   +1 more source

Homozygous Familial Hypercholesterolemia

open access: diamond, 2021
Atsushi Nohara   +13 more
openalex   +2 more sources

Complex phenotype of hypercholesterolaemia in a family with both ABCG8 and APOB mutations [PDF]

open access: yes, 2017
Familial Hypercholesterolemia (FH) is the most common of all genetic hypercholesterolaemias with defects in LDLR, APOB and PCSK9 accounting for the majority of cases.
Alves, A.C.   +7 more
core  

Dentition‐Cognition Relationship in Aging Populations: A Meta‐Analysis of Longitudinal Data

open access: yesJournal of Oral Rehabilitation, EarlyView.
Tooth loss is a risk factor for cognitive impairment in longitudinal studies. The application of dentures can alleviate the side impact of tooth loss on cognitive decline. ABSTRACT Background Recent research suggests a potential link between tooth loss and cognitive decline among the elderly population, but longitudinal evidence remains limited.
Huimin Chen   +4 more
wiley   +1 more source

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