Results 181 to 190 of about 19,814 (246)

Increased macrophage activity in coronary plaques in patients with acute coronary syndrome and familial hypercholesterolemia. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Iwaya T, Minami Y, Asakura K, Nagata T, Katamine M, Hashimoto T, Ako J.   +6 more
europepmc   +1 more source

The causal effects of hypothyroidism on cardiovascular disease: Bidirectional and multivariable Mendelian randomization study

Journal of Diabetes Investigation, Volume 17, Issue 3, Page 499-509, March 2026.
Our study suggests bidirectional causal associations between hypothyroidism and both coronary artery disease (CAD) and myocardial infarction (MI). Moreover, hypothyroidism contributes to an increased risk of peripheral atherosclerosis (PAS). ABSTRACT Background Whether hypothyroidism and cardiovascular disease (CVD) are causally related remains ...
Xuan Bai, Mengyi Sun, Xu Han
wiley   +1 more source

Opportunistic Genomic Screening for Familial Hypercholesterolemia to Improve Low-Density Lipoprotein Cholesterol: A Randomized Clinical Trial.

JAMA Netw Open
Vassy JL, Brunette CA, Yi T, Assimes TL, Christensen KD, Knowles JW, Sturm AC, Sun YV, Alexander N, Cardellino MP, Harrison A, Gerety HL, Pyatt M, Vered R, Wilson PWF, Natarajan P, Whitbourne SB, Gaziano JM, Muralidhar S, Danowski ME, Veterans Affairs Million Veteran Program.   +20 more
europepmc   +1 more source

Correction to: Evinacumab for Pediatric Patients With Homozygous Familial Hypercholesterolemia. [PDF]

Circulation
Wiegman A, Greber-Platzer S, Ali S, Doortje Reijman M, Brinton EA, Charng MJ, Srinivasan S, Baker-Smith C, Baum S, Brothers JA, Hartz J, Moriarty PM, Mendell J, Bihorel S, Banerjee P, George RT, Hirshberg B, Pordy R.   +17 more
europepmc   +1 more source

LDL Cholesterol Modulates Astrocyte Metabolism, Lipid Handling, and Morphology: Evidence From In Vitro and In Vivo Models

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
In vitro, low‐density lipoprotein cholesterol (LDL cholesterol) promotes the accumulation of lipid derivatives in astrocytes. Additionally, LDL cholesterol exposure causes a decrease in the expression of low‐density lipoprotein receptor (LDLr), 3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR), and sterol regulatory element‐binding transcription factor ...
Gabriela Joras Baumart, Matheus Scarpatto Rodrigues, Juliete Nathali Sholl, Arieli Cruz de Sousa, Augusto Ferreira Weber, Lílian Corrêa Costa‐Beber, Hémelin Resende Farias, Mariana Viana Costa, Ariadni Mesquita Peres, Pedro Rocha de Camargo, Fernanda Telles Fróes, Rachel Krolow Bast, Andreza Fabro de Bem, Fabrício Figueiró, Fátima T. C. R. Guma, Jade de Oliveira   +15 more
wiley   +1 more source

Corneal Arcus, Xanthomas, and Finger Deformities in a Young Woman With Homozygous Familial Hypercholesterolemia. [PDF]

Case Rep Med
Bagheri B, Shokri F, Farzaneh AH.
europepmc   +1 more source

Impacts of Lifestyle and Microbiota‐Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review

Obesity Reviews, Volume 27, Issue 3, March 2026.
Dietary interventions showed the strongest evidence for improving microbiome composition. Probiotics and prebiotics consistently increased beneficial bacteria. Exercise and fecal microbiota transplantation had limited evidence but showed potential for microbiome modulation.
Yee Teng Lee, Ayça Akan, Dilara Beyza Önel, Evelyn Medawar, Daria E. A. Jensen, Arno Villringer, A. Veronica Witte   +6 more
wiley   +1 more source

Triple Assessments of Atherosclerosis in Patients With Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Asia
Tada H, Kojima N, Yamagami K, Nomura A, Nohara A, Usui S, Sakata K, Kawashiri MA, Takamura M.   +8 more
europepmc   +1 more source

Differential Effects of Twice vs. Four Times Weekly Combined Exercise Training in Aging Adults With Hypertension: A Randomized Clinical Trial

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 3, March 2026.
ABSTRACT Current exercise guidelines emphasize a total weekly volume of exercise (i.e., 150 min/week), but the optimal weekly frequency remains uncertain. Therefore, this randomized clinical trial aimed to compare the effects of combined resistance and aerobic training either two or four times per week, at the same total weekly volume, on office and ...
Rodrigo Ferrari, Vinícius Mallmann Schneider, Lucas Betti Domingues, Rodrigo Abreu, Gabriel Lemes, Rodrigo Leal‐Menezes, Hirofumi Tanaka, Sandra Costa Fuchs, Leandro de Oliveira Carpes   +8 more
wiley   +1 more source

Diagnostic and Therapeutic Challenges of Homozygous and Severe Heterozygous Familial Hypercholesterolemia from Clinical Aspect-A Single-Center Study. [PDF]

J Clin Med
Nádró B, Kaluha J, Lőrincz H, Varga É, Balogh I, Harangi M.   +5 more
europepmc   +1 more source