Results 91 to 100 of about 47,001 (202)
ABSTRACT Background Infectious diseases (ID) pharmacists practice in an important therapeutic area and hold critical roles including leading antimicrobial stewardship (AMS) programs and participating in ID clinical services. High United States pharmacist burnout prevalence, before and after the coronavirus disease 2019 (COVID‐19) pandemic, ensures ...
David A. Mott +5 more
wiley +1 more source
ABSTRACT Background Exercise is a cornerstone non‐pharmacological strategy for glucose management in people with Type 1 diabetes (T1D). However, barriers such as fear of hypoglycemia and time constraints may limit participation in conventional exercise programs. Static stretching (SS) represents a low‐intensity, accessible modality that requires little
Salvatore Frenda +5 more
wiley +1 more source
Next Generation Sequencing-based subtyping and interim- and end of treatment positron emission tomography (i/eot-PET) monitoring have high potential for upfront and on-treatment risk assessment of diffuse large B-cell lymphoma patients. We performed Dana
Matías S. Mendeville +24 more
doaj +1 more source
This multicenter retrospective study of 1054 patients with NSCLC developed an interpretable Optimal Policy Survival Tree using a counterfactual random forest reward‐estimation matrix based on age, tumor diameter, and dNLR. The model identified seven patient subgroups with distinct phenotype‐associated treatment‐duration patterns: 37.8% showed more ...
Siqi Wang +14 more
wiley +1 more source
Recent Advances in Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer
Chiara Corti,1– 4 Beyza Koca,1,2 Tasnim Rahman,1,2 Elizabeth A Mittendorf,1,2,5 Sara M Tolaney1,2,6 1Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USA; 3Division of New Drugs and Early ...
Corti C +4 more
doaj
Summary Avatrombopag treatment resulted in significantly higher platelet response rates in patients when compared with placebo in a phase 3b study of patients with paediatric immune thrombocytopenia (ITP) (NCT04516967). These post hoc analyses of the 12‐week core phase further assessed the efficacy of avatrombopag, considering the influence of baseline
Rachael F. Grace +12 more
wiley +1 more source
Hematopoietic stem cell transplant does not prevent neurological deterioration in infants with Farber disease: Case report and literature review. [PDF]
Goudie C +6 more
europepmc +1 more source
The ‘Prostate Cancer Screening for People at Genetic Risk of Aggressive Disease’ (PATROL) study
Background Inherited (germline) pathogenic and likely pathogenic variants (gPVs) in key genes associated with increased risk of prostate cancer (PCa) now warrant more attentive PCa screening per National Comprehensive Cancer Network (NCCN) guidelines—e.g., BRCA2, HOXB13, ATM, BRCA1, MSH2, MSH6, CHEK2 and TP53.
Heather H. Cheng +12 more
wiley +1 more source
Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice. [PDF]
He X +7 more
europepmc +1 more source
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio +38 more
wiley +1 more source

