Results 91 to 100 of about 47,001 (202)

Factors Associated With Professional Fulfillment, Work Exhaustion, and Job Turnover Intention Among Infectious Diseases Pharmacists

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 10, October 2026.
ABSTRACT Background Infectious diseases (ID) pharmacists practice in an important therapeutic area and hold critical roles including leading antimicrobial stewardship (AMS) programs and participating in ID clinical services. High United States pharmacist burnout prevalence, before and after the coronavirus disease 2019 (COVID‐19) pandemic, ensures ...
David A. Mott   +5 more
wiley   +1 more source

Feasibility Investigation on the Effects of a 6‐Week Whole‐Body Static Stretching Program in Active Adults With Type 1 Diabetes on Blood Glucose and Insulin Sensitivity

open access: yesLifestyle Medicine, Volume 7, Issue 4, October 2026.
ABSTRACT Background Exercise is a cornerstone non‐pharmacological strategy for glucose management in people with Type 1 diabetes (T1D). However, barriers such as fear of hypoglycemia and time constraints may limit participation in conventional exercise programs. Static stretching (SS) represents a low‐intensity, accessible modality that requires little
Salvatore Frenda   +5 more
wiley   +1 more source

Integrating genetic subtypes with PET scan monitoring to predict outcome in diffuse large B-cell lymphoma

open access: yesNature Communications
Next Generation Sequencing-based subtyping and interim- and end of treatment positron emission tomography (i/eot-PET) monitoring have high potential for upfront and on-treatment risk assessment of diffuse large B-cell lymphoma patients. We performed Dana
Matías S. Mendeville   +24 more
doaj   +1 more source

Optimal, Interpretable, and Personalized Immune Checkpoint Inhibitor Duration in Non‐Small Cell Lung Cancer: A Multicenter Real‐World Study

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This multicenter retrospective study of 1054 patients with NSCLC developed an interpretable Optimal Policy Survival Tree using a counterfactual random forest reward‐estimation matrix based on age, tumor diameter, and dNLR. The model identified seven patient subgroups with distinct phenotype‐associated treatment‐duration patterns: 37.8% showed more ...
Siqi Wang   +14 more
wiley   +1 more source

Recent Advances in Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer

open access: yesImmunoTargets and Therapy
Chiara Corti,1– 4 Beyza Koca,1,2 Tasnim Rahman,1,2 Elizabeth A Mittendorf,1,2,5 Sara M Tolaney1,2,6 1Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USA; 3Division of New Drugs and Early ...
Corti C   +4 more
doaj  

Avatrombopag for persistent and chronic immune thrombocytopenia in children: A post hoc analysis of clinical characteristics of response from a phase 3b clinical trial

open access: yesBritish Journal of Haematology, Volume 209, Issue 4, Page 1818-1827, October 2026.
Summary Avatrombopag treatment resulted in significantly higher platelet response rates in patients when compared with placebo in a phase 3b study of patients with paediatric immune thrombocytopenia (ITP) (NCT04516967). These post hoc analyses of the 12‐week core phase further assessed the efficacy of avatrombopag, considering the influence of baseline
Rachael F. Grace   +12 more
wiley   +1 more source

The ‘Prostate Cancer Screening for People at Genetic Risk of Aggressive Disease’ (PATROL) study

open access: yesBJU International, Volume 138, Issue 4, Page 600-606, October 2026.
Background Inherited (germline) pathogenic and likely pathogenic variants (gPVs) in key genes associated with increased risk of prostate cancer (PCa) now warrant more attentive PCa screening per National Comprehensive Cancer Network (NCCN) guidelines—e.g., BRCA2, HOXB13, ATM, BRCA1, MSH2, MSH6, CHEK2 and TP53.
Heather H. Cheng   +12 more
wiley   +1 more source

Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice. [PDF]

open access: yesBBA Clin, 2017
He X   +7 more
europepmc   +1 more source

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

open access: yesEuropean Journal of Haematology, Volume 117, Issue 4, Page 922-935, October 2026.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio   +38 more
wiley   +1 more source

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