Results 31 to 40 of about 47,001 (202)
International Journal of Cancer, EarlyView.ABSTRACT Adjuvant chemotherapy can improve outcomes for patients who have undergone lung cancer resection, and perioperative rehabilitation may help maintain the physical condition necessary to receive adjuvant chemotherapy. This observational cohort study investigated the impact of perioperative rehabilitation on the administration of postoperative ...
Shinkichi Takamori +12 more
wiley +1 more source
Orphanet Journal of Rare Diseases, 2019 Background Hyaline fibromatosis syndrome (HFS) is a rare clinical condition in which bi-allelic variants in ANTXR2 are associated with extracellular hyaline deposits. It manifests as multiple skin nodules, patchy hyperpigmentation, joint contractures and
Claudia Cozma +15 more
doaj +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Long‐term survival data for patients with locally advanced gastro‐esophageal adenocarcinoma (GEA) treated with neoadjuvant chemoimmunotherapy are lacking. We describe the long‐term disease‐free survival (DFS) and overall survival (OS) outcomes of such patients treated with a novel neoadjuvant chemoimmunotherapy regimen, aDCF (avelumab with ...
Thierry Alcindor +8 more
wiley +1 more source
Breast Cancer: Targets and Therapy, 2022 Arun Kadamkulam Syriac,1 Nitish Singh Nandu,2 Jose Pablo Leone1 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA; 2Department of Hospice and Palliative Medicine, Montefiore Medical Center/ Albert Einstein College of ...
Kadamkulam Syriac A, Nandu NS, Leone JP
doaj
The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming
Stem Cell Reports, 2014 Reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) entails a mesenchymal to epithelial transition (MET). While attempting to dissect the mechanism of MET during reprogramming, we observed that knockdown (KD) of the epithelial-to ...
Juli J. Unternaehrer +9 more
doaj +1 more source
Journal of Clinical Psychology, EarlyView.ABSTRACT Objective The importance of being actively involved in dealing with mental health care problems is well‐recognized. Many terms and ideas have been introduced to explicate this active involvement, but to date, there is no consensus about a definition.
Ilana L. J. Buijssen +2 more
wiley +1 more source
Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders
EMBO Molecular Medicine, 2022 T cells are the current choice for many cell therapy applications. They are relatively easy to access, expand in culture, and genetically modify. Rapamycin‐conditioning ex vivo reprograms T cells, increasing their memory properties and capacity for ...
Murtaza S Nagree +8 more
doaj +1 more source
JPGN Reports, EarlyView.Abstract Objectives Shwachman–Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its endoscopic phenotype is poorly defined. We sought to characterize endoscopic findings in patients with genetically confirmed SDS. Methods Retrospective registry study of 45 patients with biallelic Shwachman–Bodian–Diamond syndrome mutations and ...
Elizabeth Korn +15 more
wiley +1 more source
Systemic ceramide accumulation leads to severe and varied pathological consequences
EMBO Molecular Medicine, 2013 Farber disease (FD) is a severe inherited disorder of lipid metabolism characterized by deficient lysosomal acid ceramidase (ACDase) activity, resulting in ceramide accumulation. Ceramide and metabolites have roles in cell apoptosis and proliferation. We
Abdulfatah M. Alayoubi +18 more
doaj +1 more source
Leucemia linfoblástica aguda na criança. Experiência de dez anos com o protocolo DFCI 81-01.
Acta Médica Portuguesa, 1999 Acute lymphoblastic leukemia is the most frequently encountered pediatric cancer. Approximately 70% of cases can be cured of the disease. In this article, we describe the experience of our Center in the last ten years with a treatment protocol adapted ...
A F de Lacerda +7 more
doaj +1 more source