Results 101 to 110 of about 15,452 (211)

Regulation of dolichol-linked glycosylation [PDF]

open access: yes, 2018
In the majority of congenital disorders of glycosylation, the assembly of the glycan precursor GlcNAc2Man9Glc3 on the polyprenol carrier dolichyl-pyrophosphate is compromised.
Welti, Michael
core  

The role of protein prenylation inhibition through targeting FPPS by zoledronic acid in the prevention of renal fibrosis in rats

open access: yesScientific Reports
Renal fibrosis (RF) represents the most widespread pathological condition in chronic kidney disease (CKD). Recently, protein prenylation has been implicated in the fibrosis’s progression. The research examined the renoprotective effect of zoledronic acid
Reham Hussein Mohamed   +7 more
doaj   +1 more source

The Enigma of Sponge-Derived Terpenoid Isothiocyanate–Thiocyanate Pairs: A Biosynthetic Proposal

open access: yesMarine Drugs
The co-occurrence of rare terpenoid thiocyanates (R-SCN), structurally similar to their more common isothiocyanate isomers (R-NCS), poses an enigma: how does the accepted path, terpenyl cation R+ → R-NC → R-NCS, accommodate R-SCN?
Tadeusz F. Molinski
doaj   +1 more source

Temporal expression of a putative homogentisate solanesyltransferase cDNA in wounded Aquilaria malaccensis, an endangered tropical tree [PDF]

open access: yes, 2017
Homogentisate prenytransferase (HPI) generally catalyses prenylation reactions in tocochromanol and plastoquinone-9 biosynthesis, while homogentisate solanesyltransferase (HST) is specific to reaction leading to plastoquinone, an essential component in ...
Anor Basah, Azzarina   +3 more
core  

Development of a Komagataella phaffii cell factory for sustainable production of ( +)-valencene

open access: yesMicrobial Cell Factories
Background Sesquiterpene ( +)-valencene is a characteristic aroma component from sweet orange fruit, which has a variety of biological activities and is widely used in industrial manufacturing of food, beverage and cosmetics industries.
Jintao Cheng   +10 more
doaj   +1 more source

Impact of protein prenylation inhibition on Mycobacterium leprae viability and IL-1β production in infected macrophages

open access: yesJournal of Bacteriology
Leprosy is a chronic infectious disease caused by Mycobacterium leprae and M. lepromatosis. Brazil consistently ranks among the countries with the highest number of leprosy cases. Data from our group showed that M.
Matheus da Silva Rocha   +11 more
doaj   +1 more source

Production Of Oligo(Cis-1,4)Isoprene In Recombinant Synechocystis Sp. Pcc 6803 Through The Insertion Of Rubber Biosynthesis-Related Genes [PDF]

open access: yes, 2016
Getah asli daripada Hevea brasiliensis secara dominannya, terdiri daripada 1,4-poliisoprena yang mempunyai lebih daripada 10,000 unit isoprena berulang (C5H8)n dalam konfigurasi cis Natural rubber of Hevea brasiliensis is composed predominantly of 1,4-
Sam , Ka Kei
core  

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